Clinical Omics – News and Features

Around 5,500 people with severe developmental disorders now know the genetic cause of their condition, thanks to a major nationwide study which will help improve diagnosis across the world.

This article will review the latest applications of mass spectrometry-based techniques across the stages of biopharmaceutical development and testing.

A team of biomedical engineers has been working to make LC-MS/MS sample preparation simpler and much more automated, a key ingredient to the technique being widely adopted by clinicians.

This article discusses how library-based approaches in quantitative proteomics can increase the sensitivity and accuracy of such detection systems.

Researchers have published an assessment of 13 studies that took a genotype-first approach to patient care that contrasts with the typical phenotype-first approach to clinical research, which starts with clinical findings.

Featuring expert insights, this article will reflect on recent progress in the multiomics research space, exploring workflow developments, technologies and applications.

A new version of the Human Protein Atlas has been released, featuring the Human Disease Blood Atlas, a pan-cancer strategy that depicts proteome signatures for specific types of cancer. The atlas was created using next-generation proteome profiling methods, and offers enthusiasm for the future of the clinical proteomics field.

Here we explore how biomarkers are driving the immuno-oncology landscape. We dive into cutting-edge biomarker research and the challenges facing the field.

Researchers have identified biological markers in triple-negative breast cancer that are associated with resistance to chemotherapy treatment.

Gas chromatography mass spectrometry (GC-MS) is an important technique in the analytical chemist's armory. In this article we explore how GC-MS and GC-MS/MS work, what they can tell us, their strengths, weaknesses and applications.