Clinical Omics – News and Features
Major Study Diagnoses 5,500 People With Rare Genetic Diseases
Around 5,500 people with severe developmental disorders now know the genetic cause of their condition, thanks to a major nationwide study which will help improve diagnosis across the world.
Applications of Mass Spectrometry in Biopharmaceutical Analysis
This article will review the latest applications of mass spectrometry-based techniques across the stages of biopharmaceutical development and testing.
New Method Developed To Monitor Antidepressants in Patients
A team of biomedical engineers has been working to make LC-MS/MS sample preparation simpler and much more automated, a key ingredient to the technique being widely adopted by clinicians.
Using Library-Based Approaches To Increase Depth and Accuracy of Proteome Profiling
This article discusses how library-based approaches in quantitative proteomics can increase the sensitivity and accuracy of such detection systems.
Genotype-First Approach Uncovers New Links to Genetic Conditions
Researchers have published an assessment of 13 studies that took a genotype-first approach to patient care that contrasts with the typical phenotype-first approach to clinical research, which starts with clinical findings.
Multiomics – A Multi-Layered Answer to Multi-Layered Questions
Featuring expert insights, this article will reflect on recent progress in the multiomics research space, exploring workflow developments, technologies and applications.
Detecting Cancer From a Droplet of Blood
A new version of the Human Protein Atlas has been released, featuring the Human Disease Blood Atlas, a pan-cancer strategy that depicts proteome signatures for specific types of cancer. The atlas was created using next-generation proteome profiling methods, and offers enthusiasm for the future of the clinical proteomics field.
Mark a Course for the Future – Biomarkers in Cancer Immunotherapy
Here we explore how biomarkers are driving the immuno-oncology landscape. We dive into cutting-edge biomarker research and the challenges facing the field.
Treatment Outcome and Resistance Markers Identified in Triple Negative Breast Cancer
Researchers have identified biological markers in triple-negative breast cancer that are associated with resistance to chemotherapy treatment.
GC-MS Principle, Instrument and Analyses and GC-MS/MS
Gas chromatography mass spectrometry (GC-MS) is an important technique in the analytical chemist's armory. In this article we explore how GC-MS and GC-MS/MS work, what they can tell us, their strengths, weaknesses and applications.