Clinical Omics – News and Features

News
Probing the Dark Matter of the Cancer Genome for Prognostic Biomarkers
Researchers have uncovered 166 prognostic biomarkers through machine learning analysis of long non-coding RNAs.

News
Insights Into Lung Tumor Biology and Potential Drug Targets
A team of researchers has developed the largest and most comprehensive molecular map to date of lung squamous cell carcinoma. The database, which brings proteomic, transcriptomic and genomic data together, can be used to find potential new drug targets and identify underlying disease mechanisms related to therapy resistance.

Article
Mass Spectrometry Brings Resolving Power to Biopharma
In the early 20th century, mass spectrometry (MS) was used to measure the mass of atoms and demonstrate the existence of isotopes. Now, MS is used to study a broad range of molecules including small hydrocarbons, proteins, peptides, carbohydrates and DNA.

News
Probing Deep Into Tumor Tissues
Researchers have analyzed more than 8,000 proteins in detail from fixed samples of lung cancer tissue using mass spectrometers.

Article
How a Mass Spectrometer Works, Types of Instrumentation and Interpreting Mass Spectral Data
Mass spectrometry (MS) is a key technique in analytical chemistry and plays a role in many varied aspects of day-to-day life. In this article, we take a look at the fundamentals of MS, how it works, variations that can be used at each stage of the process and how they can be combined to suit different sample types or analytical questions.

Article
COVID-19 Multiomics Research: Strategies, Insights and Tools
In this article, we explore multiomic approaches to COVID-19 research and explore some of the computational and statistical tools being developed to support multiomic analyses.

News
Whole Genome Sequencing Enables More Precise Diagnoses for Patients With Rare Diseases
More than 1,200 people with rare diseases have received a diagnosis thanks to the integration of large-scale genomics into the Stockholm region's healthcare system.

News
A Rapid Genomics Strategy To Trace Coronavirus
Researchers have created a rapid genome sequencing strategy for the coronavirus.

Article
Mapping the Human Proteome: A Journey
In 2020, we celebrate 90% of the human proteome being mapped by the Human Proteome Project (HPP). In this article, we reflect on the history of this endeavor and the future of the proteomics field, speaking with individuals close to the project.

News
Collaborations Aim To Meet Unmet Clinical Needs in Biomarker Discovery and Characterization
Thermo Fisher Scientific announced agreements with AstraZeneca and the University of Nebraska Medical Center that will showcase new workflows to improve the throughput, robustness and standardization of clinical biomarker analysis.
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