CRISPR and Genome Editing – News and Features

A study uncovers how H2O2-induced redox modification regulates the RNA demethylase SlALKBH2. This modification stabilizes SlALKBH2 and accelerates tomato ripening without altering its m6A demethylase activity.

Scientists at the University of Florida are testing a new type of citrus tree that can fight off the tiny insects responsible for citrus greening.

The adaptive immune system is highly complex and specific. In this article we focus on T cells, and discuss their development, their different functions, and what happens when they don't function correctly.

Penn researchers introduce mvGPT, a gene editing tool that edits DNA, activates genes and represses gene expression simultaneously. Successfully tested on cells with Wilson’s disease, mvGPT addresses multiple conditions with high precision.

Rutgers researchers highlight the role of brown adipose tissue (BAT) in boosting endurance and promoting healthy aging. BAT improves blood circulation, reduces cellular stress and enhances metabolism

ECRC researchers developed a CRISPR-based gene therapy targeting dysferlin mutations in muscular dystrophy. By editing and transplanting corrected muscle stem cells, they restored protein function and regrew muscle in preclinical models.

This article provides examples of where AI has been utilized to predict disease outbreaks and how AI models could help inform future strategies for controlling the spread of infectious diseases.

New research by Oregon Health & Science University scientists has uncovered multiple factors to improve gene delivery to the kidney by adeno-associated virus vectors.

St. Jude researchers developed a 3D atlas tracing brain connections to spinal V1 interneurons, crucial for movement. Using modified rabies virus and serial two-photon tomography, they mapped neural pathways for motor control.

University of Illinois researchers developed SPLICER, a gene editing tool enhancing exon skipping. Targeting Alzheimer’s-related genes in mice, SPLICER decreased amyloid-beta plaque precursors by 25%, outperforming CRISPR techniques.