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CRISPR and Genome Editing – News and Features

A syringe with pale pink liquid rests on two empty syringes.
News

Gene Therapy for Rare Neurodegenerative Disease Shows Promise in Trial

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy, was well tolerated and showed signs of therapeutic benefit in a clinical trial.
Cancer cells.
News

Mutation Behind Leukemia Cell Therapy Resistance Identified

Researchers at the University of Zurich and the University Hospital Zurich have discovered that a specific mutation in the cancer cells of an aggressive type of blood cancer can prevent novel immunotherapies such as CAR T-cell therapy from working.
Pills spill form a prescription bottle.
News

Issue Hampering Pancreatic Cancer Drug Combination Identified

Researchers have identified two enzymes that work against the chemotherapy drug gemcitabine, preventing it from treating pancreatic cancer.
A Native Hill Lotus plant growing between rocks.
News

Some Soil Bacteria Evolve Genes for Nickel Detoxification

A Washington State University-led research team pinpointed a set of genes in wild soil bacteria that allows them to do this in serpentine soils which have naturally high concentrations of toxic nickel.
Petri dishes in gloved hands.
News

Scientists Engineer a New Mold-Burger

Despite the unappealing origins of the fake meat, burgers derived from different fungi species have become supermarket staples in recent years thanks to rising consumer interest in environmental sustainability and meat-free lifestyles.
A person touching the genome.
News

Prime Editing Helps Scientists Screen the Effects of Cancer Mutations

Scientists at the Massachusetts Institute of Technology have developed a rapid gene-editing screen to explore the effects of cancer mutations.
T cells.
News

Why Do Some Immune Cells Lose Energy in Solid Tumors?

New research has unveiled new clues behind T-cell metabolism, that could enhance immunotherapies that rely on T cells to fight cancer.
A scientist holding a rack of tubes in a laboratory.
News

Alzheimer’s Drug Production a Step Closer With the Help of Bacteria and AI

Researchers have developed a microbial fermentation method to produce galantamine with the help of artificial intelligence (AI) and biosensors.
A DNA double helix.
News

Rapid CRISPR-Based Test for Tropical Disease Could Save Lives

CRISPR-based test detects a genetic target that is specific to Burkholderia pseudomallei, the bacterium that causes melioidosis, with 93% sensitivity.
A syringe filled with liquid is balanced on two empty syringes.
News

“Dramatic” Brain Cancer Regression in Early Results of Cell Therapy Trial

Just days after a single treatment of a new cell therapy, three glioblastoma patients experienced dramatic reductions in their tumors.
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