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CRISPR and Genome Editing – News and Features

A scientist behind a screen.
News

CRISPR Edits RNA in Living Cells

A team published research this week that shows how RNA, the close chemical cousin to DNA, can be edited using CRISPRs. The work reveals a new process in human cells that has potential for treating a wide variety of genetic diseases.
Cancer cells.
News

Biomarkers Linked to Cell Therapy Response for Bone Marrow Tumors Identified

In a recent clinical study, researchers identified several biomarkers that are associated with the response to CAR T cell therapy in multiple myeloma, a malignant tumour disease in the bone marrow.
Ribosome translating mRNA into a polypeptide chain.
Industry Insight

Tuning the Therapeutic Properties of tRNAs To Treat Rare Diseases

Michelle C. Werner discusses how tRNAs could transform the drug development paradigm from gene-centric to gene-agnostic and accelerate new therapies for 30 million or more patients whose genetically driven disease can be classified under Stop Codon Disease.
A brown and yellow cicilid fish.
News

How Curiosity Drives Evolution

Exploratory behavior is one of the fundamental personality traits of animals – and this trait can drive survival and evolution.
Two in-focus T cells with many more behind them.
News

New Tools Developed To Study Communication of Immune Cells

A new class of genetically modified mice are helping researchers to study chemokine communications between immune cells.
Cancer cells.
News

Blocking Gene May Halt Growth of Some Breast Cancers

Shutting down a gene called PRMT5 stopped metastatic estrogen receptor-positive (ER+) breast cancer cells from growing after they acquired resistance to a standard therapy known as CDK4/6 inhibitors.
A gloved hand holds a syringe filled with yellow liquid.
News

Gene Therapy Trial for Sickle Cell Disease Publishes Final Results

The final results of a clinical trial for the gene therapy CASGEVY, which was used to treat sickle-cell disease, have been published.
T cells.
News

How Do Immune Cells Communicate To Fight Viruses?

Researchers at the University Hospital Bonn (UKB) and the University of Bonn have developed a new class of genetically modified mice that enables the simultaneous identification of chemokine producers and sensors.
Schematic representation of SemaCyte microcarriers including optical barcodes.
Industry Insight

Tackling Unmet Drug Screening Needs

In this interview, Jeroen Verheyen tells us about Semarion, its SemaCyte technology and how it can help to address unmet drug screening needs.
Dividing cells.
News

Capturing Cell Division in Embryos With Timelapse Photography

With the help of medaka fish, CRISPR and new imaging techniques, researchers have set a new standard for studying cell division at the very earliest stages of life.
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