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CRISPR and Genome Editing – News and Features

Cells.
News

CRISPRmap Enables Spatially-Resolved Interrogation of Gene Function

Researchers developed CRISPRmap, an optical pooled screening approach that links the optical properties of single cells to targeted genetic perturbations. This technique enables high-throughput studies of gene function in complex tissues.
Two researchers looking into a tank.
Article

A Holistic Approach To Investigate Climate Change and Marine Neurobiology

A new, state-of-the-art research center at the Scripps Institute for Oceanography, University of California San Diego, will offer a unique window into how climate change is impacting the nervous systems of marine life.
Four women smiling.
Article

From Menstruation to Menopause: How Hormonal Shifts Shape Women's Brain Health

Recent studies highlight the unique challenges women face regarding brain health, emphasizing the influence of hormonal changes during the menstrual cycle, pregnancy and menopause on cognitive function, mood and overall well-being.
Blood collection tubes
News

CRISPR-Based Rapid Diagnostic for Gene Fusions in Leukemia

New technology that rapidly and simply detects disease-specific molecular alterations in two forms of leukemia could give many more patients access to lifesaving cancer treatments in the U.S. and in resource-limited countries.
A person stepping to an open door, as though they are walking into freedom.
Article

Almost 50% of Scientists Are Leaving Academia Within 10 Years – Here’s Why

A new study published in Higher Education has found that nearly 50% of scientists quit academia within 10 years of publishing their first paper. We asked the scientific community about their reasons for "leaving" science.
Neurons labelled with green, yellow, light blue and dark blue fluorescent staining.
News

Gene Therapy Enables Precise Magnetic Field Control of Brain Circuits

A new gene therapy technology enables the non-invasive control of specific brain circuits, holding promise for studying the brain and finding treatments for neurological conditions.
Two orange pill bottles next to a model of a human brain and a doctor writing on a clipboard.
News

Mutation Linked to Epilepsy Targeted With Novel Gene Therapy

NUS Medicine researchers are exploring a gene therapy approach for epilepsy linked to the KCNA2 mutation. The therapy uses Gapmer antisense oligonucleotides to target faulty RNA, restoring potassium flow and reducing excessive neuron activity.
A doctor holding a clipboard.
News

Gene Therapy Shows Long-Term Benefit for Rare Pediatric Brain Disease

Researchers report that 94% of patients treated with the gene therapy eli-cel for cerebral adrenoleukodystrophy (CALD) have maintained neurological function six years post-treatment.
A strand of DNA.
News

Enzyme Engineered To Produce Threose Nucleic Acid, a Synthetic Genetic Material

Researchers have engineered an enzyme to produce synthetic genetic material, advancing the discovery of new therapeutics for cancer and autoimmune, metabolic and infectious diseases.
RNA Polymerase II transcribing DNA into RNA.
Industry Insight

Getting New Drug Modalities to Market: How Can Your Data Strategy Help?

This article explores the revolution in new drug modalities and the challenges around effective data strategies to support AI efforts.
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