CRISPR and Genome Editing – News and Features

In this article, we explore the evolution of drug repurposing from a serendipitous occurrence to a more formalized endeavor involving advanced computational approaches and bioengineered test beds, considering its advantages, challenges and successes.

Children carrying a variant of the SCN2A gene, which is associated with severe ASD, were found to have a hypersensitive VOR in a new study. The researchers believe this finding could pave the way for faster diagnosis and innovative treatments.

Biomedical researchers have developed a new, less expensive way to detect nuclease digestion – one of the critical steps in many nucleic acid sensing applications, such as those used to identify COVID-19 and other infectious diseases.

While traditional methods of cell sorting come with several challenges, microbubbles are simple to use and can separate cells without causing harm. Technology Networks spoke to Dr. Brandon McNaughton, CEO and co-founder of Akadeum to find out more about this technology, its applications and how it could improve cancer treatment.

A new study from the Krumlauf laboratory shows that the hindbrain of humans and jawless sea lamprey is built using a similar molecular and genetic toolkit. This discovery implies that these molecular features were present in the common ancestor of all vertebrates today.

In this interview, John Finn tells us more about PGI, how it compares to other genome editing approaches and the benefits it could bring to genomic medicine discovery.

Researchers from the Salk Institute have uncovered a protein complex that regulates gene expression during sperm production and discovered an oral non-hormonal drug that reversibly stops this process in mice, without obvious side effects.

Researchers have uncovered a link between the spread of antibiotic resistance in humans and livestock genes and the evolution of drug resistance in pathogens.

Using the new cell culture model "iNets", University of Zurich researchers identified a missing link between aberrant TDP-43 behavior and neuronal cell death: a toxic accumulation of NPTX2, a protein that is usually secreted through the synapses.

A new approach uses a retrotransposon from birds to insert genes into "safe harbors" in the genome, holding promise for gene therapy.