Drug Kinetics – News and Features
PET Scans Can Measure the Impact of STING-Activating Drugs in Cancer
Findings from a study suggest that positron emission tomography (PET) imaging could provide a widely accessible approach to measure the pharmacodynamic effects of using stimulator of interferon genes (STING)-activating drugs.
New Long-Acting Injectable Drug Delivery System for Tuberculosis
In 2020, more than 1.5 million people died of tuberculosis (TB). Now, researchers have developed a TB drug that showed potential with just one injection that lasts at least four months, improving on current treatment which requires daily medication.
Targeted Immunotherapy Developed for Direct Injection Into Tumors
A new method of delivering an immunotherapy directly to a tumor has been developed, composed of a gelatin/nanoplatelet mixture for effective drug delivery and sustained drug release.
Drug Delivery “Bottleneck” Identified in Stem Cells
In a recent study, researchers shed some light on why the delivery of therapeutics to cells can be so difficult.
How Different Cancer Types Respond to Nanoparticle Drug Delivery
Study findings could help researchers better tailor their drug-delivery particles to specific types of cancer, or design new particles that take advantage of the biological features of particular types of cancer cells.
Light Controlled Neutrophils Perform Multiple Tasks in Living Fish
For the first time, researchers have used lasers to precisely control neutrophils — a type of white blood cell — as a natural, biocompatible microrobot in living fish.
Tuneable Microparticles Could Be Used To Deliver “Self-Boosting” Vaccines
MIT researchers have developed microparticles that can be tuned to deliver their payload at different time points, which could be used to create “self-boosting” vaccines.
New Screening Technique Could Accelerate mRNA Therapy Development
Researchers have developed a system to make studies on mRNA therapies and their lipid nanoparticle delivery systems more predictive using a technique called DNA barcoding.
An Introduction to Electroporation – A Tool for Transfection and Competent Cell Generation
There are many reasons you may want to deliver something into a cell, be it genetic material or a therapeutic drug, and electroporation is a vital tool to achieve this. In this article, we will consider what electroporation is, how it works and how it’s used.
What’s the Best Way To Take 5-MeO-DMT in a Clinical Trial?
Beckley Psytech recently announced that they have dosed the first healthy volunteers in their Phase I trial of an intranasally delivered formulation of 5-MeO-DMT, named BPL-003. To find out more about their trial approach and wider research into 5-MeO-DMT, we spoke to Beckley’s chief scientific offer, Dr. Steve Wooding.