Drug Kinetics – News and Features

Findings from a study suggest that positron emission tomography (PET) imaging could provide a widely accessible approach to measure the pharmacodynamic effects of using stimulator of interferon genes (STING)-activating drugs.

In 2020, more than 1.5 million people died of tuberculosis (TB). Now, researchers have developed a TB drug that showed potential with just one injection that lasts at least four months, improving on current treatment which requires daily medication.

A new method of delivering an immunotherapy directly to a tumor has been developed, composed of a gelatin/nanoplatelet mixture for effective drug delivery and sustained drug release.

In a recent study, researchers shed some light on why the delivery of therapeutics to cells can be so difficult.

Study findings could help researchers better tailor their drug-delivery particles to specific types of cancer, or design new particles that take advantage of the biological features of particular types of cancer cells.

For the first time, researchers have used lasers to precisely control neutrophils — a type of white blood cell — as a natural, biocompatible microrobot in living fish.

MIT researchers have developed microparticles that can be tuned to deliver their payload at different time points, which could be used to create “self-boosting” vaccines.

Researchers have developed a system to make studies on mRNA therapies and their lipid nanoparticle delivery systems more predictive using a technique called DNA barcoding.

There are many reasons you may want to deliver something into a cell, be it genetic material or a therapeutic drug, and electroporation is a vital tool to achieve this. In this article, we will consider what electroporation is, how it works and how it’s used.

Beckley Psytech recently announced that they have dosed the first healthy volunteers in their Phase I trial of an intranasally delivered formulation of 5-MeO-DMT, named BPL-003. To find out more about their trial approach and wider research into 5-MeO-DMT, we spoke to Beckley’s chief scientific offer, Dr. Steve Wooding.