This page provides educational resources, events, news and products related to drug targets. Content will cover aspects from identification and validation of new drug targets, to therapeutic development and the benefits to health.
Drug Targets – Highlights
The Changing Landscape of Target-Based Drug Discovery
In this article, we discuss the cost of developing a drug, what makes a good drug target, the challenges and benefits of target-based drug discovery and how target-based approaches compare to phenotypic led approaches.
Expediting Drug Discovery Using Novel Target-Based Approaches
This article covers some strategies that can be harnessed to develop new therapeutic candidates not achievable with the current approaches.
Discovering Druggable Targets
We recently spoke to Dr Kilian V. M. Huber from the Structural Genomics Consortium & Target Discovery Institute, University of Oxford to find out – ‘What makes a good target?’.
Newly Discovered Brainstem Circuit Knocks Out Nausea
A new study in mice describes how different cell types in the brain work together to suppress nausea.
Computer Model Identifies Mutations That Drive Cancer Growth
MIT researchers have built a new computer model that can rapidly scan the entire genome of cancer cells and identify mutations that occur more frequently than expected, suggesting that they are driving tumor growth.
Interpreting Tumor “Signatures” May Lead to Better Treatments and Survival
Scientists have found a way to interpret "signatures" in the chromosomes of tumors, revealing the genetic causes of cancers with some of the lowest survival rates. This may lead to more accurate treatments and improved survival.
New Brain-Permeable Drug Targets Melanoma Brain Metastases
Researchers have demonstrated striking preclinical efficacy of a BRAF inhibitor, C1a, that can cross the blood–brain barrier and has potent activity against melanoma metastases in the brain.
Blood Test Pinpoints Colon Cancer Patients Needing Chemotherapy
A novel blood test that assesses levels of circulating tumor DNA can identify patients who require chemo after surgery.
Dolomite Bio Releases Hydrogel Reagent Kits for Agarose Encapsulation and 3D Cell Culture Research
Dolomite Bio launches new hydrogel-focused reagent kits, enabling high-throughput encapsulation of cells in hydrogel scaffolds.
NanoTemper Technologies Launches Spectral Shift
NanoTemper Technologies has announced the launch of Spectral Shift technology within their Dianthus instrument, built to handle the most challenging affinity-based screenings in drug discovery.