Drug Targets – News and Features

University of Wisconsin–Madison researchers revealed how gut microbial bile acids impact colon cancer. One bile acid slows tumor growth by supporting the FXR protein, while another accelerates cancer by inhibiting it.

This article explores some of the challenges in developing cell lines for therapeutics, such as cell line stability, and how they are being addressed.

Professor Jennifer Van Eyk joined Technology Networks for an exclusive interview at HUPO 2024 to discuss progress and bottlenecks in clinical proteomics

New potential therapeutic targets have been identified for diabetic kidney disease, the leading cause of kidney failure worldwide.

Researchers have shed new light on how Toxoplasma gondii parasites make the proteins they need to evade drug treatment.

University of Alabama researchers reveal a key mechanism in BK polyomavirus replication, challenging existing models. The virus relies on host cell DNA replication, with its TAg protein expressed only after the first replication round.

A novel computational pipeline has been designed to identify protein biomarkers associated with complex diseases, including Alzheimer’s disease.

A new study confirms that an "Alzheimer's in a dish" model can mimic brain function and gene expression patterns, making it ideal for assessing new drugs as well as finding new targets.

RNA therapeutics promise rapid, personalized and flexible treatments against multiple diseases. In this article, we will explore whether RNA therapeutics can realize their full potential.

Researchers have used whole-genome CRISPR interference screening to identify the “Achilles Heel” of drug-resistant tuberculosis and identify drugs that target these weaknesses to rapidly kill drug-resistant strains.