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Gene and Cell Therapy – News and Features

A thin electronic sensor on a gloved finger.
News

New “Smart Bandages” Have Potential to Revolutionize the Treatment of Chronic Wounds

"Smart bandages" that can automatically sense and respond to changes in a wound could revolutionize chronic wound treatment, including diabetic ulcers and surgical wounds.
A COVID-19 protein.
News

Why Don’t Some People Get COVID-19?

Using single-cell sequencing technology, researchers provide the most comprehensive timeline to date of how the body responds to SARS-CoV-2 exposure.
Disc-shaped red blood cells.
News

Gene-Editing Therapy Yields Positive Results for Sickle Cell Patients

An experimental one-time gene-editing cell therapy for sickle cell disease has shown promise in trials.
Three T cells surround a cancer cell
News

Secondary Cancer Risk Low Following CAR T-Cell Therapy, Study Finds

New research illustrates that the risk of secondary cancers following CAR T-cell therapy is low.
Cancer cells.
News

Enhancing CAR-T Cell Therapies With Biodegradable Scaffolds

T-cell stimulating biomaterial that slowly biodegrades under the skin stimulates CAR-T cells in the body to improve therapeutic efficacy in an aggressive mouse tumor model.
Double helix structure of DNA.
News

Enhanced Gene Editing System Enables Therapeutic Gene-Sized Edits in Human Cells

The gene-editing approach uses prime editors and evolved enzymes called recombinases, and could pave the way to effective one-size-fits-all gene therapies for diseases such as cystic fibrosis.
Image of a virus showing the spike proteins on the surface of the virus
News

Immune System “Misdirection” May Explain Link Between Epstein-Barr Virus and MS

Research from the University of Birmingham has found that following EBV infection there is more immune system cross-reactivity, where the body’s immune system binds to the wrong target, than previously thought.
Stem cells.
News

Gut Stem Cell Research Reveals Mistaken Cellular Identity

Two independent studies by Columbia scientists suggest that research into the gut’s stem cells over the past 15 years has been marred by a case of mistaken identity: Scientists have been studying the wrong cell.
Red blood cells flow through a blood vessel.
News

Discovery of the “Missing Piece” Behind Blood Stem Cell Self-Renewal Could Improve Transplant Availability

Scientists have identified a protein that plays a critical role in regulating human blood stem cell self-renewal by helping them sense and interpret signals from their environment.
A hand holding a test tube in front of a 3D structure of a DNA helix.
News

Bilateral Gene Therapy Restores Hearing in Children with Inherited Deafness

A new clinical trial in Shanghai, China, in partnership with Mass Eye and Ear researchers, demonstrated the restoration of hearing in both ears in five children born with autosomal deafness caused by mutations in the OTOF gene.
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