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Gene and Cell Therapy – News and Features

Stem cells with textured nuclei and transparent membranes.
News

Squeezing Through Narrow Spaces Prompts Stem Cells To Turn Into Bone Cells

In a discovery that could reshape approaches to regenerative medicine and bone repair, researchers have found that human stem cells can be prompted to begin turning into bone cells simply by squeezing through narrow spaces.
Purple and pink neurons against a black background.
News

Magnetic Nanoparticles Steer Brain Cells To Rebuild Lost Connections

Researchers have developed a novel approach that uses magnetically guided mechanical forces to direct axonal growth, aiming to enhance the effectiveness of stem cell-based therapies for Parkinson's disease and other neurological conditions.
The outline of a liver, filled with interconnected dots illustrating vasculature and the connection between cells.
News

Scientists Improve Liver Organoids for Research Into Hemophilia

Researchers have created liver tissue that grows its own blood vessels, improving research into hemophilia and liver damage.
Illustration of pink chromosomes on a blue background.
News

Why Humans Are More Susceptible to Cancer

Researchers at the University of California Davis Comprehensive Cancer Center have uncovered an evolutionary change that may explain why human immune cells are less effective at combating solid tumors compared to our closest living ancestors.
Illustration of stem cells being injected by syringe for regenerative stem cell therapy.
News

Patterned Culture Dish Elevates Stem Cell Therapy Potential

Researchers developed a method to grow mesenchymal stem cells as aligned sheets using a patterned culture dish. This setup increases secretion of key cytokines linked to healing and immune regulation.
3D digital representation of a DNA strand, symbolizing the CRISPR gene-editing technology.
News

CRISPR Tool Accounts for Genetic Variability To Improve Predictions

A new tool, Variant-aware Cas-OFFinder, enhances CRISPR-Cas9 predictions by factoring in genetic variations like SNPs and deletions. It provides more accurate, personalized genome editing strategies for humans and plants.
Close-up of red blood cells in motion, illustrating their role in the circulatory system.
News

Mutations in Blood Stem Cells May Protect Against Alzheimer’s

Researchers at Baylor College of Medicine discovered that mutations in the TET2 gene in blood stem cells could protect against late-onset Alzheimer’s disease. The study showed that TET2-mutant cells help clear beta-amyloid plaques.
Neurons form connections between themselves.
News

Dystroglycan Plays a Key Role in Connections Between Nerve Cells

New research reveals that the protein Dystroglycan plays a critical role in forming and maintaining connections between nerve cells in the cerebellum.
Close-up of a prosthetic human ear, symbolizing the concept of deafness or hearing loss.
News

OTOF Gene Therapy Successfully Improves Hearing in Clinical Trial

Researchers tested a gene therapy that restored partial hearing in patients with OTOF gene mutations causing congenital deafness. The therapy delivered a functional OTOF gene using an adeno-associated virus (AAV) injection.
A cancer cell being destroyed by two T cells, representing cancer immunotherapy.
News

“Leukemia-on-a-Chip” Offers a New Tool for Screening CAR T-Cell Therapy

Researchers have pioneered a novel 3D platform that mimics the human bone marrow and immune environment, enabling more predictive testing of cancer immunotherapy success in patients, including CAR T cell therapies.
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