Gene and Cell Therapy – News and Features

Researchers have identified a mechanism that causes neurological problems in mice infected with the virus behind COVID-19, and also found a treatment that helped prevent these changes.

A new quick and precise technique for producing artificial human chromosomes has been developed, which could be used to power advanced gene therapies.

An investigational gene therapy for a rare neurodegenerative disease that begins in early childhood, known as giant axonal neuropathy, was well tolerated and showed signs of therapeutic benefit in a clinical trial.

Researchers at the University of Zurich and the University Hospital Zurich have discovered that a specific mutation in the cancer cells of an aggressive type of blood cancer can prevent novel immunotherapies such as CAR T-cell therapy from working.

Findings from scientists at St. Jude Children’s Research Hospital and The University of Tennessee Health Science Center suggest T-cell therapy could effectively treat fibrolamellar carcinoma.

New research has unveiled new clues behind T-cell metabolism, that could enhance immunotherapies that rely on T cells to fight cancer.

Just days after a single treatment of a new cell therapy, three glioblastoma patients experienced dramatic reductions in their tumors.

Targeting two brain tumor-associated proteins—rather than one—with CAR T cell therapy shows promise as a strategy for reducing solid tumor growth in patients with recurrent glioblastoma (GBM), an aggressive form of brain cancer.

Discover how genetic tuning differs from gene editing and other modalities of genetic medicine and how the ability to fine-tune genes will transform precision medicine.

Featuring research from the Doudna laboratory, the University of Harvard and the Center for Advanced Bioenergy and Bioproducts Innovation, this round-up piece discusses the latest research advancements in CRISPR technology.