Gene and Cell Therapy – Webinars and Online Events

Ancillary materials (AMs), also called raw materials in Europe, are components, reagents, and materials used in the manufacturing of cell, gene, and tissue-engineered (CGT) therapies but are not intended to be present in the final product formulation.

In this webinar, Dr. Kristin G. Anderson, Research Associate from the Greenberg lab at the Fred Hutchinson Cancer Research Center, discusses engineering T cells to improve survival in the immunosuppressive tumor microenvironment.

Cell therapy is a transformative cancer treatment that utilizes genetically modified cells from a healthy donor or patient's own immune system to attack cancer cells, but manufacturing these cells represents a major challenge for the industry.

With the rapid increase in the development of oligonucleotide therapeutics and gene therapies, workflows for the identification, characterization and quantification of full-length products, their impurities and metabolites, are critical.

Current regulatory authorities (WHO, EMA and US FDA) limited the accepted amounts of residual DNA in biological products making it extremely important to have a sensitive method of quantifying residual host cell DNA. Among the methods of detecting residual DNA, qPCR is the most widely used for residual DNA quantitation due to its sensitivity, accuracy, precision, and time-saving capability.

New trends and challenges are being identified as more cell and gene therapy institutions move toward clinical trials and into commercialization. Closed manufacturing systems are designed to minimize contamination risks and reduce ISO cleanroom requirements. In combination with digital connectivity, these systems enable repeatable, trackable, and GMP-compliant manufacturing processes.

By attending this webinar, you will learn regulatory guidelines for process-related impurities in cell & gene therapy products, how to identify and quantify protein impurities by SWATH LC-MS for process consistency and product purity and more.

Attend this event to hear how technology is revolutionizing nucleic acid detection and quantification in the latest science topics.

During this webinar, we will discuss our hiPSC-derived cortical and sensory neurons, co-culture and their electrophysiological characterization using microelectrode arrays (MEA). The focus is on the development of disease models, co-culture, pharmacology and neurotoxicity screening.

During this webinar, we will discuss our hiPSC-derived cardiomyocytes and a custom service we provide for their electrophysiological characterization using microelectrode arrays (MEA). The focus is on the development of disease models and cardiotoxicity screening.