This page provides educational resources, events, news and products related to light microscopy techniques and applications, including fluorescence, phase contrast, confocal and super-resolution microscopy.
Light Microscopy – Highlights
What is Super-Resolution Microscopy? STED, SIM and STORM Explained
Scientists can now use super-resolution microscopy to directly observe living subcellular structures and activities. In this piece, we explore the basics of three popular super-resolution techniques.
Bioimaging Using Microscopes: Challenges, Benefits and the Future
The imaging of biological samples, or bioimaging, plays a key role in current life science research, enabling scientists to analyze molecules, cells and tissues from a range of living systems.
An Introduction to the Light Microscope, Light Microscopy Techniques and Applications
Today, light microscopy is a core technique in many areas of science and technology. In this article, we explore the basic working principle of light microscopy and discuss some more advanced forms of light microscopy that are commonly used today, comparing their strengths and weaknesses for different applications.
Best Practices for 3D Cell Imaging With Dr. Ann Rossi Bilodeau
In this Teach Me in 10, Dr. Ann Rossi Bilodeau talks about the best practices for 3D cell imaging, whether tissue clearing reagent can be used to clear spheroids expressing fluorescent proteins and we learn more about the new 3D Clear Tissue Clearing reagent from Corning Life Sciences.
Protein “Molecular Zipper” Could Be Targeted for Retinitis Pigmentosa Therapy
A "molecular zipper" that forms microtubules in photoreceptor cells could provide a new drug target for retinitis pigmentosa, the most common hereditary retinal disease in people.
Transplanted Human Cells Restore Light Perception in Mice
Dresden scientists developed a robust method to produce a high number of human photoreceptor cells and used them to restore daylight perception in mice with degenerated eyesight.
Study Reveals How Cells Form Vesicles To Transport Cargo Like Growth Factors
Advanced fluorescence microscopy imaging has shown how cells form vesicles, resolving the conflict between existing models of how the vesicles form.
Species-Specific Differences in Neuron Architecture Explored Using Microscopy
Researchers have found that primates and non-primates differ in an important aspect of their architecture: the origin of the axon which is the process responsible for the transmission of electrical signals.
Imaging Organoids With Light-Sheet Fluorescence Microscopy
Studying tissue and organ biology is challenging, particularly in mammals, given sample accessibility and ethical concerns. However, the use of organoids alleviates these challenges, supporting researchers in exploring questions that previously could not have been investigated without them.
TrueLive3D Imager Light-Sheet Microscope
Optimized for fast 3D multi-sample volume imaging of delicate live specimen in their native 3D environment, the TruLive3D Imager is especially suited for multi-position imaging of small embryos (e.g., mouse), 3D spheroids, organoids, oocytes and more, enabling time-lapse, high-throughput imaging experiments.
Sartorius Unveils LIVECell, a Deep-Learning Dataset for Label-Free, Quantitative Cell Segmentation
Sartorius has announced the publication of an article in Nature Methods describing the company’s LIVECell (Label-free In Vitro image Examples of Cells) deep-learning dataset for label-free, quantitative segmentation of live cell images.