Light Microscopy – News and Features

See-through zebrafish have given researchers the opportunity to test a novel imaging method that provides insights into the inner workings of the blood stem cell environment.

Scientists are looking into how embryonic exposure to certain common pollutants may put people at risk for diabetes and other metabolic health conditions later in life.

The decisions made by cells – such as whether to divide – are made based on both extracellular signals and signals from within the cell, according to new research.

University of Zurich researchers found that single cells make decisions much more autonomously than previously thought.

This article discusses the use of NMR to investigate protein structure and dynamics in neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.

Immunohistochemistry exploits antigen–antibody binding to study the status of target molecules in tissues of interest. In this article, we explore how it works, factors that impact experimental design and its applications.

A "molecular zipper" that forms microtubules in photoreceptor cells could provide a new drug target for retinitis pigmentosa, the most common hereditary retinal disease in people.

Dresden scientists developed a robust method to produce a high number of human photoreceptor cells and used them to restore daylight perception in mice with degenerated eyesight.

A new technique to analyze biomolecules has been developed and could enable promising drug candidates to be identified at an earlier stage in the drug development pipeline.

Advanced fluorescence microscopy imaging has shown how cells form vesicles, resolving the conflict between existing models of how the vesicles form.