Light Microscopy – News and Features
Novel Imaging Method Provides High-Resolution View of Single Blood Stem Cells in Zebrafish
See-through zebrafish have given researchers the opportunity to test a novel imaging method that provides insights into the inner workings of the blood stem cell environment.
Could Prenatal Exposure to Environmental Pollutants Increase the Risk of Diabetes?
Scientists are looking into how embryonic exposure to certain common pollutants may put people at risk for diabetes and other metabolic health conditions later in life.
Individual Cells Are Smarter Than We Thought
The decisions made by cells – such as whether to divide – are made based on both extracellular signals and signals from within the cell, according to new research.
Individual Cells Are Smarter Than Previously Thought
University of Zurich researchers found that single cells make decisions much more autonomously than previously thought.
NMR for Biomolecule Conformations and Drug Discovery in Neurodegenerative Diseases
This article discusses the use of NMR to investigate protein structure and dynamics in neurodegenerative diseases such as Alzheimer’s disease and Parkinson’s disease.
Immunohistochemistry Techniques, Strengths, Limitations and Applications
Immunohistochemistry exploits antigen–antibody binding to study the status of target molecules in tissues of interest. In this article, we explore how it works, factors that impact experimental design and its applications.
Protein “Molecular Zipper” Could Be Targeted for Retinitis Pigmentosa Therapy
A "molecular zipper" that forms microtubules in photoreceptor cells could provide a new drug target for retinitis pigmentosa, the most common hereditary retinal disease in people.
Transplanted Human Cells Restore Light Perception in Mice
Dresden scientists developed a robust method to produce a high number of human photoreceptor cells and used them to restore daylight perception in mice with degenerated eyesight.
Nanochannels Light the Way Towards Developing New Drugs
A new technique to analyze biomolecules has been developed and could enable promising drug candidates to be identified at an earlier stage in the drug development pipeline.
Study Reveals How Cells Form Vesicles To Transport Cargo Like Growth Factors
Advanced fluorescence microscopy imaging has shown how cells form vesicles, resolving the conflict between existing models of how the vesicles form.