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Multiomics – News and Features

DNA damage in cells shown using a fluorescent microscope.

Antioxidant Enzymes Repair DNA Damage

In crisis, the nucleus calls antioxidant enzymes to the rescue. The nucleus being metabolically active is a profound paradigm shift with implications for cancer research.
A person putting sweetener in their drink.

Artificial Sweetener Metabolite Breaks DNA

Scientists at the North Carolina State University found that a chemical compound produced through the digestion of a common artificial sweetener causes damage to DNA.
Cartoon showing how viral particles can spread from person to person when in close contact.

Novel Multiomics Approach Uncovers Why Flu Severity Varies Between Individuals

Have you ever wondered why some people might get sicker than others, even when they catch the same virus? It is not yet clear why this is.
The ovarian tumor microenvironment, shown in blue and green.

Subtypes for Difficult-To-Treat Ovarian Cancer Identified

Three subtypes of a difficult-to-treat ovarian cancer have been identified, based on differences in intracellular signaling pathways. This finding could help researchers to develop more effective therapies.
A doctor in a lab coat, with a strand of DNA and a microscope in the background.

New High-Efficiency Assay Promises Speedy Mitochondrial Disease Diagnosis

A rapid, efficient assay system for validating gene variants linked to mitochondrial diseases has been developed by researchers in Japan.
A woman spraying a tree with pesticide.

10 Pesticides Linked With Damage in Parkinson's Neurons

Researchers have identified 10 pesticides that significantly damaged neurons implicated in the development of Parkinson’s disease.
A teaspoon of sweetener. The sweetener spills over a grey surface.

Human Immune Cells React to Non-Nutritive Sweeteners

Non-nutritive sweeteners, commonly used in diet drinks, have been shown to impact gene expression in white blood cells, which researchers suggest may sensitize the immune cells to certain stimuli.
The Madagascar periwinkle of the dogbane family alongside the skeletal formula of vincristine and vinblastine.

New Insights Into Natural Product Biosynthesis Revealed

Single-cell multiomics reveals that cell types are differentially involved in the production and accumulation of medically relevant plant compounds.
A doctor looks at an X-Ray of a torso.

Blood Test May Predict Responses to Chemoimmunotherapy

A newly identified biomarker can indicate which patients with non-small cell lung cancer will respond well to chemoimmunotherapy
A woman standing with a cartoon drawing of an interestine drawn on her.

Edible Capsule Maps the Hidden Microbiome in Our Upper Intestine

New research has utilized a custom capsule to study a previously hard-to-reach area of the gut, potentially opening up a whole new area of study into the chemicals and microorganisms that live there