Multiomics – News and Features

A study of infants and young children found those who acquired SARS-CoV-2 had a strong, sustained antibody response to the virus and high levels of inflammatory proteins in the nose but not in the blood.

The COVID-19 pandemic seemed like a never-ending parade of SARS-CoV-2 variants, leaving the world bracing for what would come next. But what if there were a way to make predictions about new viral variants before they actually emerge?

A groundbreaking study has shed light on the intricate mechanism behind the immune system’s ability to differentiate between self and non-self antigens.

Becoming a full-fledged organism out of a handful of cells, complete with functioning tissues and organs, is a messy yet highly synchronized process that requires cells to organize themselves in a precise manner and begin working together.

In this op-ed, Markus Gershater delves into different aspects of the data we’ll need to generate to help us truly understand the biological systems we deal with.

Pooled promoter responses to TF perturbation sequencing (PPTP-seq) is a new technique that integrates CRISPR gene editing with a combinatorial library containing every known transcription factor in the target genome and corresponding promoters.

By developing an efficient way to compare all predicted protein structures in the AlphaFold database, researchers have revealed similarities between proteins across different species.

Relatively little was known about the mechanisms underlying how these mutated HSCs expand to cause cancer. In the current study researchers from the University of Oxford explored how chronic inflammation has a previously unknown effect on TP53-mutant HSCs in cancer development.

Patient responses to glucagon-like peptide 1 (GLP-1R) agonist drugs – used to treat type 2 diabetes and obesity – may depend on variations in GLP-1R genes, according to a new study.

A new study has examined the cause-and-effect relationship between depression and type 2 diabetes, revealing that depression directly causes an increased risk of developing type 2 diabetes.