Multiomics – News and Features

Bacteria live in nearly every habitat on earth including within soil, water, acidic hot springs and even within our own guts. But scientists don’t understand a fundamental process within bacterial cells: how they organize themselves before division.

A new study shows that intermittent fasting and calorie restriction change the microbiome diversity in the gut, which could impact other functions in the body.

Scientists have identified how low levels of the TET2 gene fuel the rapid growth of acute myeloid leukemia in animal models.

Deep analysis of the proteins that drive multiple cancer types reveals information that can’t be assessed by standard genome sequencing alone, and opens avenues for new therapies that block these driving mechanisms.

A technique that enables scientists to record gene mutations and patterns of gene activity in individual cells has been extended to cover RNA splicing as well.

To try to get ahead of future outbreaks and prevent congenital developmental disorders caused by such neurotropic viruses, a team set out to better understand how Zika affects the developing brain.

Scientists have employed a computer model to identify a network in the tuberculosis pathogen that allows it to tolerate drug therapies, which could result in the development of more effective drugs.

Para-cresol has a strong horse stable-like odor, which can contribute to the off-flavor of some foods, including cocoa and olive oil. A cellular test system has revealed the human receptor for para-cresol.

A new study has constructed an “aging clock” for the female body – information missing from previous studies of aging. The research mapped 4 domains of biological aging – chronic inflammation, hormonal regulation, tissue fitness and lipid metabolism – that can together accurately measure female biological age.

Through genetic analyses, a collaborative research team has shown that a 46,000-year-old roundworm discovered in the Siberian Permafrost is a previously undescribed species. The research is published in PLoS Genetics.