This page provides educational resources, events, news and products related to next-generation sequencing techniques and applications, including sequencing technologies and DNA and RNA-based techniques utilizing anything from cultures and tissues, to single cells and environmental samples.
Next-Generation Sequencing – Highlights
Download this infographic to learn about whole-exome sequencing (WES) vs whole-genome sequencing (WGS), a classical WES workflow and how WES can be used in the pursuit of personalized medicine.
RNA-Seq: Basics, Applications and Protocol
RNA-seq (RNA-sequencing) is a technique that can examine the quantity and sequences of RNA in a sample using next-generation sequencing (NGS). Here, we look at why RNA-seq is useful, how the technique works, a basic protocol that is commonly used today and challenges that remain.
An Overview of Next-Generation Sequencing
Over the last 56 years, researchers have been developing methods and technologies to assist in the determination of nucleic acid sequences in biological samples. Our ability to sequence DNA and RNA accurately has had a great impact in numerous research fields. This article discusses what next-generation sequencing (NGS) is, advances in the technology and its applications.
How To Guide
How To Address NGS Challenges
Download this guide to learn how to select the appropriate NGS method and sequencing platform, deal with samples of variable quality, and set up and manage the data analysis pipeline.
Teach Me in 10 – Molecular and Cellular Multiplexing With Professor George Church
In this instalment of Teach Me in 10, Professor George Church, a pioneer of genomics and synthetic biology, treats us to a topic that he hasn't actually presented on publicly before: molecular and cellular multiplexing.
Malaria Parasites Sync Their Molecular Rhythms With Those of Their Host
Research could pave the way to new anti-malarials that work by “jet-lagging” the parasites that cause the disease.
Antibiotic Resistance Identified in Places Where It Was Previously Unseen
Antibiotic resistance genes are more widespread in our environment than previously thought, with new research indicating bacteria in almost all environments carry resistance genes.
Older Trees Contribute to Genetic Diversity More Than Short-Lived Trees
A study demonstrated that long-lived tropical trees accumulate more somatic mutations, providing insights into potential mechanisms underlying genetic variation.
Pigmented Rice Enhancements Could Help To Combat Malnutrition
Scientists have shown that desirable agronomic traits of shorter stem length and early maturity can be introduced into black rice, which is known to be more nutritious than white rice.
DNA Sequencing in Newborns Reveals Years of Actionable Findings for Infants and Families
Researchers who lead the world’s first comprehensive sequencing program for newborn infants have published the next chapter in the ongoing study of the BabySeq Project, with new findings on infants and families who have been followed for 3-5 years.
Deepcell Launches AI-Powered Single Cell Analysis Platform
Deepcell has announced the launch of the REM-I Platform, a high-dimensional cell morphology analysis and sorting platform which comprises the REM-I benchtop instrument, Human Foundation Model and Axon data suite.
Pharmacogenomics Research Could Save NHS at Least £41 Million Annually
An analysis of NHS prescriptions data has revealed the huge potential for pharmacogenomics to reduce ineffective prescribing and adverse effects, which could save millions of pounds for the NHS.