Next-Generation Sequencing – Multimedia
Poster
Refining Liquid Biopsy: Generating More Information From Cell Free DNA
Liquid biopsy for profiling of cell free DNA (cfDNA) in blood holds huge promise to transform how we experience and manage cancer by early detection and identification of residual disease and subtype. However, a standard blood draw yields an average of only 10 ng of cfDNA, of which DNA derived from the tumor is a small minority.
How To Guide
A Guide to Sample Preparation for Next-Generation Sequencing
Download this guide to explore tips on how to avoid issues during NGS experiment design, tissue/specimen handling and isolation of nucleic acids.
Poster
Whole Transcriptome Expression of FFPE Samples
Formaldehyde fixed & paraffin-embedded (FFPE) tissue blocks are one of the most commonly used and archived sample types. However, some preservation approaches can result in the degradation of RNA and hinder transcriptome profiling .
eBook
Whole-Genome Sequencing: Small Genomes
The ability to characterize microbial genomes is advancing many fields of research. In fact, sequencing approaches now allow scientists to understand disease origins and anticipate transmission patterns with applications across human health, farming and food production industries.
Video
An Overview of NGS Adapters for Ligation-based Library Preparation
In this Teach Me in 10 we are joined by senior field application scientist Nick Hapshe.
Listicle
Recent Applications of Proteomics
Download this listicle to explore how proteomics is being applied in drug discovery and biomedical research, food industry, agriculture, environmental science and forensics.
eBook
Advances in Cancer Research
In this eBook, we highlight developments in cancer research through a selection of articles, interviews and graphics.
Video
Revealing the Combinatorial Power of Genetic and Epigenetic Information for Early Cancer Detection
In this episode we discuss how the combination of both genetic and epigenetic information within a single DNA sample can provide key insights on the dynamic interactions that are occurring, offering significant advantages in many research areas.
Video
Unlocking the Potential of Genetics and Epigenetics for Early Cancer Detection
In this Teach me in 10 episode we will explore how simultaneous sequencing of genetic and epigenetic bases in cfDNA allows for early cancer detection.
eBook
A Primer on NGS Adapters: Structural Elements, Key Functions and Workflow Differences
Unique molecular identifiers (UMIs) now present a solution that can reduce quantitative bias, distinguish between PCR duplicates, and recognize sequencing errors.
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