Next-Generation Sequencing – Multimedia

Oxford Nanopore’s long-read cDNA sequencing solutions allow researchers to sequence millions of whole transcripts end-to-end in single reads. This enables users to simultaneously perform accurate isoform-level transcriptome characterisation, and differential gene expression profiling without any of the compromises on cost, quantitation, computational or workflow complexity required to achieve this on other short or long read sequencing platforms.

To really understand how cells develop over time, snapshots aren't good enough: scientists want to fill in the gaps between snapshots and string everything together into a movie. Therefore, researchers are tapping into a powerful 18th century mathematical method called "optimal transport."

In this infographic, we look at what the tumor microenvironment is, the cells and factors that comprise it, how single-cell sequencing can be used to investigate it, and the therapeutics that target it.

Genomic sequencing is a process for analyzing a sample of DNA taken from your blood. In the lab, technicians extract DNA and prepare it for sequencing.

PromethION offers the same real-time, long-read, direct DNA and RNA sequencing technology as MinION and GridION, on a much larger scale.

Get a new perspective on your sample QC with the Agilent 4150 TapeStation system and open up new horizons. Ideal for handling smaller numbers of samples, the system with ScreenTape assays delivers fast, reliable results within any NGS workflow.

The retrospective identification of the drug targets that underlie an observed phenotypic response is termed target deconvolution. This list highlights five approaches that can be applied to target deconvolution.

When Single Molecule, Real-Time (SMRT) sequencing was first released, it promised a huge shift in our approach to sequencing – moving away from methods that had up to that point been validated and entrenched in labs across the world. In this guide, PacBio's Nick Sisneros provides some insight into SMRT Sequencing and the tips and tricks that will ensure success in the template prep and sample preparation for use on this sequencing platform.

For most laboratory workflows, you’re only as good as your starting material. This is particularly true for next-generation sequencing (NGS). Here are several tips and tricks to preparing NGS libraries that hold true across all applications.

Plate-based scRNA-seq approaches are advantageous for the in-depth analysis of rare cell types and subpopulations selected by cell surface markers.