Next-Generation Sequencing – Multimedia
Poster
Is Oxford Nanopore Technology Ready for Clinical Diagnostics?
Our objective is to validate diagnostic services using Oxford Nanopore’s Minion in the first instance and to evaluate the cost and performance compared to existing sequencing technology in areas such as tumour DNA sequencing (and circulating tumour DNA), virology, microbiology, genetics and HLA-typing.
Infographic
Challenges in Genetic Data Management
Genomics is a big data science and is going to get much bigger, very soon. With data storage facilities already struggling to keep up, many believe that the challenges of genetic data management are only just beginning.
Poster
Performance of the D5000 and High Sensitivity D5000 ScreenTape Assays for the 4200 TapeStation System
Here, we focus on quantification, sizing, and sensitivity of both D5000 ScreenTape assays.
Poster
Comparison of the Biological Effects of Long-Term Exposure of Human Bronchial Epithelial Cells to Total Particulate Matter from 3R4F Cigarette Smoke or Aerosol from the Candidate Modified Risk Tobacco Product (cMRTP) THS2.2
We mimicked chronic exposure in smokers’ airways by continuously exposing BEAS-2B cells to TPM from 3R4F cigarette smoke or aerosol of the Tobacco Heating System 2.2 (THS2.2), a cMRTP, for 12 weeks.
Poster
Genomic Analysis of L5178Y tk+/- Cells and their Induced tk-/- Mutant Colonies
The goal of this pilot study was to exploit NGS technology with a view to shedding new light on the genome of cells used in the MLA, as well as the changes induced as a result of the exposure to mutagens.
Video
Integration of High Throughput ‘Omic Platforms into Antibody Discovery
In pursuit of lead structures, ‘omic technologies are revolutionizing the discovery and development of novel biological lead structures.
Poster
Highly Accurate HCV Genotyping by Targeted Next Generation Sequencing
The recent fast advancement of next generation sequencing (NGS) technologies allowing for unprecedented speed and accuracy in analyzing viral genomes are opening new ways to further improve diagnostic genotyping of HCV.
Poster
Ion Torrent next generation sequencing for accurate genotyping and detection of resistance associated variants in HCV and HIV
Objectives: to develop improved detection of clinically relevant viral mutations using ion torrent based NGS in an automated workflow.
Video
Next-Gen Sequencing Animation
Next-generation sequencing in a simple animation.
Poster
Workshop Report: Bioinformatics Meets Digital Pathology
Pathologists are the guardians of large quantities of high-resolution
imaging material, that is barely noticed by bioinformatics today. Yet this (annotated) material can be of huge contributing value to any research project, as pathology preserves topological tissue features, and can help explain difficult phenomena such as tumor heterogeneity. The goal is then to bridge research methods and materials from the bioinformatics community with the (digital) pathology community.
imaging material, that is barely noticed by bioinformatics today. Yet this (annotated) material can be of huge contributing value to any research project, as pathology preserves topological tissue features, and can help explain difficult phenomena such as tumor heterogeneity. The goal is then to bridge research methods and materials from the bioinformatics community with the (digital) pathology community.
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