Next-Generation Sequencing – News and Features

The largest and most comprehensive cell map of the human lung has been announced, revealing the great diversity of cell types in the lung and key differences between health and disease.

A study of the DNA of more than 55,000 people worldwide has shed light on how we maintain healthy blood sugar levels after we have eaten, with implications for our understanding of how the process goes wrong in type 2 diabetes.

Researchers find that pre-basophil and mast cell progenitors differentiate into pre-basophils before producing mature basophils in mice.

Research could pave the way to new anti-malarials that work by “jet-lagging” the parasites that cause the disease.

Antibiotic resistance genes are more widespread in our environment than previously thought, with new research indicating bacteria in almost all environments carry resistance genes.

Genome sequencing of new strains of West Nile virus has indicated there are a variety of strains circulating, and may help scientists predict where different strains may appear.

A study demonstrated that long-lived tropical trees accumulate more somatic mutations, providing insights into potential mechanisms underlying genetic variation.

Scientists have shown that desirable agronomic traits of shorter stem length and early maturity can be introduced into black rice, which is known to be more nutritious than white rice.

Researchers who lead the world’s first comprehensive sequencing program for newborn infants have published the next chapter in the ongoing study of the BabySeq Project, with new findings on infants and families who have been followed for 3-5 years.

Researchers find a link between bipolar disease and potentially pathogenic mosaic mutations found in neurodevelopmental disorder genes and mitochondrial tRNA genes.