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Next-Generation Sequencing – News and Features

A pair of glasses and ball point pen laying on top of a folded newspaper with the headline "Research & Development".
Industry Insight

Why Good Science Is Key to Good Technology

In this opinion piece, Philipp Koellinger explores the changes required to level the playing field and accelerate both scientific and technological progress.
DNA helices with interconnected data points behind.
News

Long-Read Sequencing and AI Shed Light on DNA Replication

Combining long-read DNA sequencing with a predictive artificial intelligence model has provided new insights into DNA replication.
Bacteria bloom on a petri dish.
News

Genomics Data Reveals Microbial Diversity Hotspots

New research has taken stock of of the current state of microbial genomic biodiversity, finding diversity hotspots.
Illuminated ATGC letters in blue squares representing next-generation sequencing.
Industry Insight

How SPRQ Chemistry Is Breaking Barriers in DNA Sequencing

Dr. Aaron Wenger tells us about SPRQ chemistry, highlighting its unique benefits and role in expanding our understanding of rare diseases.
The outline of a liver, with interconnected dots within.
News

Rare Liver Cancer’s Unique Characteristics Identified

New insights into fibrolamellar hepatocellular carcinoma could lead to new drugs and significantly improved health outcomes.
A clinician with a stethoscope and a tablet.
News

Genetic Reanalysis Helps Diagnose Over 500 Patients

More than 500 European patients with unknown conditions have received a diagnosis through new genetic research.
A 3D graphical representation of a number of Rotavirus virions.
News

Role of Rotavirus Protein in Gastrointestinal Disease Severity Revealed

Researchers revealed that the rotavirus NSP4 protein drives disease severity by disrupting calcium signaling in infected and nearby cells. These disruptions worsen symptoms and trigger immune responses.
HIV cells attacking a human cell.
News

HIV-1's Secret RNA Structures Offer Clues for Fighting the Virus

Researchers mapped HIV-1’s translation strategy, revealing RNA elements like uORFs, iORFs and an intricate frameshift site structure that regulate viral protein synthesis. These findings highlight ribosome pausing as a key mechanism.
B cells.
News

Infection-Triggered Autoimmune Disease Driven by Mutations in “Rogue” Immune Cells

Garvan Institute researchers discovered how chronic hepatitis C virus (HCV) infections lead to autoimmune diseases like cryoglobulinemic vasculitis. By identifying rogue B cell clones caused by persistent antibody clustering and mutations.
Bacteria living the the gut.
News

Microbiome Changes Reveal Risk for Sexually Transmitted Disease

A study involving Black and Hispanic women identified two BV subtypes, with one significantly raising chlamydia risk. Advanced microbiome analysis linked specific bacterial imbalances to subsequent chlamydia infections.
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