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Next-Generation Sequencing – News and Features

Potatos.
News

Calcium Boosts Potato Plant Resistance to Bacterial Wilt

Scientists have discovered that calcium plays a significant role in enhancing the resistance of potato plants to bacterial wilt. This disease causes worldwide losses of potatoes costing $19 billion per year.
A person uses an inhaler.
News

Identification of Drivers of Chronic Allergic Inflammation Could Offer Relief to Allergy Sufferers

The discovery of a T-cell subtype that drives chronic inflammation for allergy sufferers could be the groundwork for new therapies targeting these cells.
Person jogging with the sun behind them.
News

Adopting a Healthy Lifestyle Can Offset Genetic Risks by 60%

The first-of-its-kind study assessed the health data of 353,742 people from the UK Biobank to determine how their lifestyle habits and genes affected their health.
Dr. Sarah Teichmann standing next to a building and pond.
Article

From School Science Club to Cell Atlasing With Dr. Sarah Teichmann

In this interview, Dr. Sarah Teichmann shares insights into her research interests, the goals and progress of the HCA to date, as well as her thoughts on how women can begin and build successful careers in science.
An immune cell.
News

Novel Method for Studying Protein Modifications Provides Insights Into T-Cell Activity

Researchers have used a new method to shed light on proteins that form complex signaling pathways in disease-fighting T cells and their modifications.
A scientist holds a vial of blood in a gloved hand.
Article

Advances in Liquid Biopsies: Improving Sensitivity and Earlier Detection

This article will focus on some of the advances currently being made in the field of liquid biopsy, from attempts to improve the sensitivity of tests, to using bodily fluids other than blood.
Cancer cells.
News

Biomarkers Linked to Cell Therapy Response for Bone Marrow Tumors Identified

In a recent clinical study, researchers identified several biomarkers that are associated with the response to CAR T cell therapy in multiple myeloma, a malignant tumour disease in the bone marrow.
Cancer cells.
News

Pre-Ketone Supplement With Immunotherapy Shows Promise for Prostate Cancer in Mice

Adding a pre-ketone supplement – a component of a high-fat, low-carb ketogenic diet – to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer.
Illustration of a human form
Article

Dissecting the Proteome To Understand Disease

Proteomics provides insights into the regulation of biological processes and mechanisms of disease. In this article, we explore approaches scientists are using to find early markers of disease, new drug targets and strategies to overcome resistance to treatments.
A bright image depicting neuronal connections.
News

BARSeq Reveals the Brain Is Like a Pointillism Painting

BARseq, a high-throughput sequencing method, allows scientists to read and localize RNA barcodes in situ. In a new Nature study, researchers from the Allen Institute for Brain Science applied BARseq to explore how peripheral inputs shape the cellular composition of cortical neurons.
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