Pharmacovigilance – Multimedia
Erections Gone Wrong: What Viagra Does to the Penis
In this video, Jonathan from the Institute of Human Anatomy discusses how Viagra works to assist with erectile dysfunction.
Some Sugar Free Gummy Bears Are Laxatives. No, Really
Sugar free gummies are delicious, low on calories, and… technically laxatives? Reactions producer Andrew dives into the science to figure out how he can make delicious sugar free gummies without the uncomfortable side effects.
In Vitro Approaches To Risk Assess Chemical-Mediated Changes in Thyroid Function
The hypothalamic-pituitary-thyroid axis (HPT axis) is conserved across vertebrate evolution. Perturbation of thyroid hormone homeostasis (THH) can lead to adverse effects in thyroid function affecting growth, metabolism and cognitive function.
Tackling Cardiotoxicity During Drug Development
Download this infographic to learn about the adverse effects that drugs can have on the cardiac tissue and discover new strategies to minimize and manage this risk.
A stem cell-derived heart muscle cell. Proteins that are important for muscle cell contraction are highlighted in red and green, and cell nuclei are blue.
Key Factors To Accelerate Drug Discovery
Speaking at Drug Discovery & Development online symposium 2021, Pei Liu from GenScript, presented her talk on monoclonal antibodies.
Five Ways To Measure Immunotherapy Potency
This listicle highlights five commonly used cell viability assays and their benefits and limitations in immunotherapy potency testing.
Gene Therapy To Treat Epilepsy With Dr. Eric Wengert
In this Teach Me in 10 episode, Lucy Lawrence is joined by Dr. Eric Wengert, postdoctoral fellow at The Children’s Hospital of Philadelphia to discuss gene therapies used to treat epilepsy.
Evaluating Immune Cell Therapy Potency
Download this eBook to learn more about the tools available for evaluating immune cell therapy potency.
Role of Sulfotransferases in Drug Metabolism and Potential for Drug Drug Interactions
Continuing our series on non-CYP-mediated metabolism pathways, we will be discussing another of the most requested enzymes: Sulfotransferases (SULTs). SULTs participate in Phase 2 metabolism of xenobiotics in humans and are characterized by the abundance and broad tissue distribution of the enzymes. Gene regulation and genetic polymorphism of SULTs also contribute to our understanding of the significance of these enzymes in the process of drug development.