Pharmacovigilance – News and Features

Research suggests that a common chemotherapy drug could carry a toxic inheritance for children and grandchildren of adolescent cancer survivors.

Researchers have designed cancer-fighting nanoparticles that deliver both a chemotherapy drug and a novel immunotherapy that can shrink colon and pancreatic tumors in mice.

For oncology, plant-based anti-cancer drugs have proven instrumental in the fight against a disease that claims approximately 609,360 lives in the United States alone. But their demand far outweighs their supply. Can yeast help?

A recent study analyzed the adverse effects reported by users of the hallucinogenic tea, ayahuasca. In this Ask the Researcher, we spoke with the lead author of the study Dr. Daniel Perkins about the key findings and their implications for public health.

Duke Cancer Institute researchers have identified potential biomarkers that predict the likelihood for checkpoint inhibitor drugs to backfire, driving hyper-progression of melanoma cells instead of unleashing the immune system to fight them.

Researchers have identified and developed a new drug candidate that has the potential for effectively treating temporal lobe epilepsy by suppressing neuroinflammation.

New structural insights into the tankyrase protein, which plays a key role in driving bowel cancer development, could pave the way towards better and less toxic cancer drugs.

CAR T therapy has been shown to be successful as a cancer treatment, with the potential to treat many more conditions. A new study has shown that CAR T cell therapy can be used to treat the autoimmune disease lupus.

A recent study from Weill Cornell Medicine has indicated that a new approach that targets a protein that coordinates gene expression could help treat mantle cell lymphoma.

Consuming food and beverages containing flavonols might help to slow the rate of cognitive decline, researchers from Rush University suggest.