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Pharmacovigilance – News and Features

A hand holding a half-smoked cigarette.

Existing Drugs That May Help People Quit Smoking Identified by Machine Learning

Researchers have used machine learning to identify genes related to smoking behaviors and find existing medications that may be able to be repurposed to help people quit smoking.
A pair of white gloved hands draw liquid from a vial into a syringe.

New Design Principles To Improve Cancer Vaccines

New vaccine design principles that are based on adjusting the structural location of an adjuvant and the antigen on a nanoscale vaccine have been shown to greatly increase cancer vaccine performance.
An image of sperm.

New Male Contraceptive Reduces Sperm Count by 45% in Mice

A new molecule could offer non-hormonal contraceptive options for people who produce sperm, according to new research published in The American Chemical Society (ACS)’s Journal of Medicinal Chemistry.
A person in a red shirt hugging their dog.

New Therapy Extends Lives of Dogs With Terminal Cancer

A new study has described a novel chemo- and immunotherapy that has proven to be a promising treatment for dogs with cancer.
An electron micrograph of a Marburg virus particle (blue) attaching to the surface of an infected cell (orange).

Vaccine Against Marburg Virus Shows Promise in Human Study

A newly published paper shows that an experimental vaccine against Marburg virus (MARV) was safe and induced an immune response in a small, first-in-human clinical trial.

New Guidelines Aim To Prevent Heart Problems in Children Undergoing Cancer Treatment

The world’s first international clinical guidelines to help prevent and treat heart complications in children undergoing cancer treatment have been created.
Infographic showing how the timing of radiotherapy with white blood cell production throughout the day impacts therapy efficacy.

Radiotherapy Is More Effective in the Afternoon for Female Lymphoma Patients, Study Suggests

A new study suggests that female patients with a type of lymphoma respond better to radiotherapy when treated in the afternoon than in the morning.
Face on image of a UV light source.

Air Quality May Be impaired by UV Disinfection Lamp Use

Measurements indicate that whenever UV lamps used for disinfection were switched on, both gas and small particle concentrations increased considerably, not returning to their original levels until 30 to 40 minutes after the lamps were switched off.
Radioactive symbol.
Industry Insight

The Case for RRx-001 as a Radiation Countermeasure

This article overviews the science behind the potential use of RRx-001as a “radiation buster” with anti-inflammatory and anti-free radical properties to prevent or reduce both GI-ARS and H-ARS.
An illustration of a bottlebrush-shaped nanoparticle that can be loaded with multiple drugs.

Bottlebrush-Shaped Nanoparticle Targets Cancers With Multiple Drugs

Using bottlebrush-shaped nanoparticles that can be loaded with multiple drugs, researchers calculated and delivered the optimal ratio of three cancer drugs used to treat multiple myeloma.