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Pharmacovigilance – News and Features

A doctor and patient stand and sit near an MRI machine.

Trial Shows MRI-Guided Radiotherapy Improves Treatment for Localized Prostate Cancer

According to a clinical trial, MRI-guided radiotherapy produces fewer side effects and better quality of life for patients with localized prostate cancer than computed tomography-guided radiotherapy.
A collection of white pills laid on a blue background.

New Study Brings Us a Step Closer to Creating Better Pain Medications

Scientists have created detailed structures of the human opioid receptors to guide the development of more targeted pain medications.
A woman holds the back of her neck.

Key Mechanism Involved in Nerve Pain Identified

After a decade of research, a group of scientists has succeeded in describing a mechanism associated with the production of neuropathic pain, opening an window for the development of targeted therapies.
A brain.

Why a Rare Type of Epilepsy Can Affect Consciousness

Children with absence epilepsy experience brief staring spells, during which they temporarily lose consciousness. Using a genetic model known as Genetic Absence Epilepsy Rats of Strasbourg (GAERS), researchers have identified the neuronal basis for this condition.
Representation of ovaries and the uterus.

Genetic Test Identifies Ovarian Cancer Patients Likely To Benefit From PARP Inhibitors

Researchers have developed an optimized genetic test for ovarian cancer, which helps accurately target an effective but expensive medication.
An older woman sitting in a chair.

New Alzheimer’s Drug Lecanemab Granted Accelerated Approval

The US Food and Drug Administration has given a new Alzheimer’s drug the green light. The compound, lecanemab (Leqembi) is a monoclonal antibody (mAb), part of a new class of treatments that target the underlying mechanism of disease. It was approved using the FDA’s accelerated approval pathway.
An images of drugs in different shapes and sizes.

Machine Learning Accelerates Drug Formulation Development

One of the first studies using machine learning techniques to design drug formulations has shown promise for reducing the time and cost associated with drug development.
T cells attached to a cancer cell.

Cytokine-Labeled T Cells Boost Cancer Immunotherapies

Researchers have developed a nanotechnology-driven solution to locally enhance T-cell functions without producing unwanted systemic side effects.
A syringe and vial of COVID-19 vaccine lie on a blue surface.

Low Concern and Political Distrust Contribute to Vaccine Hesitance

A study suggests that an unwillingness to accept a COVID-19 vaccine can be due to both a lack of concern for the consequences of contracting the virus and a lack of faith in the government’s actions.
Representation of human cells.

Optimized Device for Growing Mini-Organs in a Dish Developed

Engineers create a device that enables intestinal organoids to develop to unprecedented levels of maturity.