Pharmacovigilance – News and Features
Trial Shows MRI-Guided Radiotherapy Improves Treatment for Localized Prostate Cancer
According to a clinical trial, MRI-guided radiotherapy produces fewer side effects and better quality of life for patients with localized prostate cancer than computed tomography-guided radiotherapy.
New Study Brings Us a Step Closer to Creating Better Pain Medications
Scientists have created detailed structures of the human opioid receptors to guide the development of more targeted pain medications.
Key Mechanism Involved in Nerve Pain Identified
After a decade of research, a group of scientists has succeeded in describing a mechanism associated with the production of neuropathic pain, opening an window for the development of targeted therapies.
Why a Rare Type of Epilepsy Can Affect Consciousness
Children with absence epilepsy experience brief staring spells, during which they temporarily lose consciousness. Using a genetic model known as Genetic Absence Epilepsy Rats of Strasbourg (GAERS), researchers have identified the neuronal basis for this condition.
Genetic Test Identifies Ovarian Cancer Patients Likely To Benefit From PARP Inhibitors
Researchers have developed an optimized genetic test for ovarian cancer, which helps accurately target an effective but expensive medication.
New Alzheimer’s Drug Lecanemab Granted Accelerated Approval
The US Food and Drug Administration has given a new Alzheimer’s drug the green light. The compound, lecanemab (Leqembi) is a monoclonal antibody (mAb), part of a new class of treatments that target the underlying mechanism of disease. It was approved using the FDA’s accelerated approval pathway.
Machine Learning Accelerates Drug Formulation Development
One of the first studies using machine learning techniques to design drug formulations has shown promise for reducing the time and cost associated with drug development.
Cytokine-Labeled T Cells Boost Cancer Immunotherapies
Researchers have developed a nanotechnology-driven solution to locally enhance T-cell functions without producing unwanted systemic side effects.
Low Concern and Political Distrust Contribute to Vaccine Hesitance
A study suggests that an unwillingness to accept a COVID-19 vaccine can be due to both a lack of concern for the consequences of contracting the virus and a lack of faith in the government’s actions.
Optimized Device for Growing Mini-Organs in a Dish Developed
Engineers create a device that enables intestinal organoids to develop to unprecedented levels of maturity.