Pharmacovigilance – News and Features

A new study has challenged the idea that higher amounts of amyloid in the brain is an underlying cause of Alzheimer's disease, instead indicating fibrillary amyloid may be a better indicator of brain health.

Using an approach that simultaneously modifies multiple sites in fungal genomes, scientists coax fungi into revealing their best-kept secrets, ramping up the pace of new drug discovery.

Polystyrene-derived nanoplastics have been found to facilitate the formation of manganese oxide, which can affect the fate and transport of organic contaminants in natural and engineering water systems.

New evidence suggests that a 50-year-old blood pressure drug could find a new purpose as a treatment to mitigate the often life-altering effects of PTSD.

A comprehensive study detailing variations in drug responses across different subtypes of childhood acute lymphoblastic leukemia could provide a blueprint to further individualize therapy.

A three-dose malaria vaccine has demonstrated safety and efficacy when tested in adults in West Africa.

Researchers have explored a new way of administering medications that do not require injections, and instead could be as easy as swallowing a pill.

According to research, a bacterium called Lacticaseibacillus rhamnosus HA-114 prevents neurodegeneration in the C. elegans worm used to study amyotrophic lateral sclerosis (ALS).

People with a blistering skin disease called dystrophic epidermolysis bullosa often suffer from large open wounds that last for years or decades. A double-blind, placebo-controlled clinical trial of a gene therapy gel developed at Stanford Medicine shows improved wound healing in people with the disease.

There remains an active debate within the psychedelic community about the importance of psychedelic experiences to these drugs’ therapeutic effects. Delix Therapeutics is developing compounds, called psychoplastogens, that act similarly to psychedelic compounds at the molecular level but do not induce hallucinations. We spoke with the Delix team to find out more about their research's progress.