RNA-Seq – News and Features

Japanese researchers found that melanin can protect or worsen hereditary hearing loss depending on genetic context. In mice lacking the SLC26A4 gene, pigment buildup caused immune activation and inflammation in the inner ear.

Explore how multiomics research combines genomics, proteomics, and transcriptomics to offer new insights in disease modeling and therapeutic advancements.

A study from Karolinska Institutet reveals that new neurons continue forming in the adult hippocampus, the brain's memory hub. The researchers confirmed the presence of dividing neural progenitor cells across ages 0 to 78.

Researchers have identified a rare cell type and the signaling pathway behind how lung damage from toxins like wildfire smoke or respiratory viruses is repaired.

Researchers have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse embryonic fibroblasts without using stem cell technology, slashing the time needed to do this.

A study used single-cell transcriptomics to analyze maternal–fetal interfaces in six mammalian species. The team discovered ancient, conserved gene signatures linked to placental development.

Researchers have developed a bioengineered hydrogel platform capable of preserving patient-derived tumor tissues for longer periods, a breakthrough that could enhance drug testing for abdominal cancer.

Paraphase – a computational tool that accurately resolves and analyzes paralogous genes – unlocks the difficult-to-analyze regions of the genome, providing deeper insights into genetic variation, disease mechanisms and population diversity.

New cutting-edge software developed in Melbourne can help uncover how the most common heart tumor in children forms and changes. The technology has the potential to further our understanding of other childhood diseases, according to a new study.

A new discovery could help point toward the first effective therapy being discovered for triple-negative breast cancer.