RNA-Seq – News and Features

Researchers present a novel approach to single-cell RNA sequencing (scRNA-seq) called “Live-seq”, which enables the extraction of mRNA from single cells without killing the cell. The method is published in Nature.

State-of-the-art bioinformatics has enabled an international research team to uncover the complexity and high degree of conservation of the bone marrow microenvironment that regulates blood stem cells.

Researchers have developed a method to detect circulating tumor cells in the blood, using microfluidic chips to reveal clues about cancer metastasis that could lead to earlier and more targeted treatment.

According to a murine study, a hormone secreted by fat cells can restrain the growth of liver tumors.

Spatial transcriptomics has been used to create a cross-sectional map of a whole prostate, revealing a greater range of genetic variation between healthy and cancerous cells than was previously thought to exist.

Findings from a study suggest that positron emission tomography (PET) imaging could provide a widely accessible approach to measure the pharmacodynamic effects of using stimulator of interferon genes (STING)-activating drugs.

New genetic analyses of wild baboons in southern Kenya reveals that most of them carry traces of hybridization in their DNA. As a result of interbreeding, about a third of their genetic makeup consists of genes from another, closely-related species.

Analyzing the diversity of RNA transcripts in human tissues has enabled researchers to characterize how differences in genes and the environment manifest in the transcriptome.

New research describes how the human thymus generates the list of friendly proteins that T cells should not attack.

In this interview, Rolland Carlson, PhD, CEO of Immunexpress, discusses sepsis and the company’s FDA cleared SeptiCyte® RAPID test, as well as a take on the company’s differentiated value and outlook.