RNA-Seq – News and Features
New Method for RNA-Sequencing in Single Cells – Without Killing the Cell
Researchers present a novel approach to single-cell RNA sequencing (scRNA-seq) called “Live-seq”, which enables the extraction of mRNA from single cells without killing the cell. The method is published in Nature.
Cells Regulating Blood Stem Cell Maintenance Are More Diverse Than Expected
State-of-the-art bioinformatics has enabled an international research team to uncover the complexity and high degree of conservation of the bone marrow microenvironment that regulates blood stem cells.
New Chip Could Lead to Targeted and Earlier Treatments for Metastatic Cancer
Researchers have developed a method to detect circulating tumor cells in the blood, using microfluidic chips to reveal clues about cancer metastasis that could lead to earlier and more targeted treatment.
Hormone From Fat Cells Restrains Tumor Growth in Mice
According to a murine study, a hormone secreted by fat cells can restrain the growth of liver tumors.
Individual Tumors Contain a Previously Unknown Range of Genetic Variation
Spatial transcriptomics has been used to create a cross-sectional map of a whole prostate, revealing a greater range of genetic variation between healthy and cancerous cells than was previously thought to exist.
PET Scans Can Measure the Impact of STING-Activating Drugs in Cancer
Findings from a study suggest that positron emission tomography (PET) imaging could provide a widely accessible approach to measure the pharmacodynamic effects of using stimulator of interferon genes (STING)-activating drugs.
Baboons Borrowed One Third of Their Genes From Cousins
New genetic analyses of wild baboons in southern Kenya reveals that most of them carry traces of hybridization in their DNA. As a result of interbreeding, about a third of their genetic makeup consists of genes from another, closely-related species.
Mapping RNA Diversity Across Human Tissues
Analyzing the diversity of RNA transcripts in human tissues has enabled researchers to characterize how differences in genes and the environment manifest in the transcriptome.
How the Thymus Trains T Cells When To Attack or Hold Off
New research describes how the human thymus generates the list of friendly proteins that T cells should not attack.
A Paradigm Shift in Sepsis Diagnostics
In this interview, Rolland Carlson, PhD, CEO of Immunexpress, discusses sepsis and the company’s FDA cleared SeptiCyte® RAPID test, as well as a take on the company’s differentiated value and outlook.