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RNA-Seq – News and Features

immunofluorescent staining shows a lymph node that has been significantly expanded in mice with the help of the biomaterial MPS-vaccine (on the right), next to a lymph node taken from non-treated control mice (on the left) at the same time post-vaccination.

Biomaterial Vaccine Enhances Lymph Node Expansion and Boosts Anti-Tumor Immunity

A biomaterial vaccine enhances and sustains lymph node expansion following vaccination, boosting anti-tumor immunity in an animal model.
A colorized scanning electron micrograph of a malaria parasite infecting a red blood cell.

Insights Into Malaria Parasites Sexual Development Reveals Opportunities To Prevent Disease Spread

For the first time, the developmental stages of the deadliest human malaria parasite have been mapped in high resolution, revealing opportunities to prevent the spread of disease.
A researcher wearing gloves holds a petri dish containing cell culture medium.

Study of 400 ALS Patients Reveals Epigenetic Risk Factors

Epigenetic analysis of 400 ALS patients has revealed 30 locations with modifications that appear linked to ALS progression.

Calcium Boosts Potato Plant Resistance to Bacterial Wilt

Scientists have discovered that calcium plays a significant role in enhancing the resistance of potato plants to bacterial wilt. This disease causes worldwide losses of potatoes costing $19 billion per year.
A person uses an inhaler.

Identification of Drivers of Chronic Allergic Inflammation Could Offer Relief to Allergy Sufferers

The discovery of a T-cell subtype that drives chronic inflammation for allergy sufferers could be the groundwork for new therapies targeting these cells.
A scientist holds a vial of blood in a gloved hand.

Advances in Liquid Biopsies: Improving Sensitivity and Earlier Detection

This article will focus on some of the advances currently being made in the field of liquid biopsy, from attempts to improve the sensitivity of tests, to using bodily fluids other than blood.
Cancer cells.

Pre-Ketone Supplement With Immunotherapy Shows Promise for Prostate Cancer in Mice

Adding a pre-ketone supplement – a component of a high-fat, low-carb ketogenic diet – to a type of cancer therapy in a laboratory setting was highly effective for treating prostate cancer.
Illustration of a human form

Dissecting the Proteome To Understand Disease

Proteomics provides insights into the regulation of biological processes and mechanisms of disease. In this article, we explore approaches scientists are using to find early markers of disease, new drug targets and strategies to overcome resistance to treatments.
A bright image depicting neuronal connections.

BARSeq Reveals the Brain Is Like a Pointillism Painting

BARseq, a high-throughput sequencing method, allows scientists to read and localize RNA barcodes in situ. In a new Nature study, researchers from the Allen Institute for Brain Science applied BARseq to explore how peripheral inputs shape the cellular composition of cortical neurons.
Multimodal analyses of cells from abnormal tunnels in Crohn's disease converge to illuminate underlying pathomechanisms.

Single-Cell Analysis Reveals Mechanism of Common Crohn’s Disease Complication

Study identifies key pathways underlying perianal fistula, a complication that is more prevalent and severe in African American populations.