Screening Strategies in Drug Discovery
This page provides educational resources, events, news and products related to screening strategies in drug discovery. Content will cover aspects including fragment-, cell- and target-based screening, high-throughput screening, phenotypic screening and virtual screening.
Screening Strategies in Drug Discovery – Highlights
The Role of Phenotypic Screening in Drug Discovery
There is an ever-growing curiosity in the potential benefit of combining phenotypic and genomic data, in the quest to advance small-molecule drug discovery. Understanding the advantages and challenges of phenotypic screening will help enhance its value as a tool for identifying drug candidates.
Fragment-Based Drug Discovery
In this infographic, we review the history of fragment-based drug discovery, discuss the underlying concepts and examine the process in more detail.
Advances in Fragment-Based Drug Discovery
Over the past decade, fragment-based drug discovery has garnered increasing interest among drug discovery experts and has established itself as a key approach within the field – acting as an alternative starting point for the discovery of high-quality lead candidates. This article discusses the evolution of FBDD, highlights key drug discoveries, and explores the advantages and challenges of harnessing this approach
Fragment-Based Drug Discovery Enters the Mainstream
This article will discuss the principles of fragment-based drug discovery and will highlight some examples of recent successes in this area.
Artificial Sweetener Metabolite Breaks DNA
Scientists at the North Carolina State University found that a chemical compound produced through the digestion of a common artificial sweetener causes damage to DNA.
"Molecular Editing" Technique Aids Crafting of Pharmaceuticals and Other Compounds
Researchers add another powerful tool to their “molecular editing” kit for crafting pharmaceuticals and other valuable compounds, enabling chemists to add new elements to organic molecules at locations that were previously out of reach.
Recent Advances in Therapeutic Antibody Screening
This article explores the various screening technologies used in the development of therapeutic antibodies and outlines the recent advances in this area.
New RNA Degrader Approach Tackles the “Mount Everest” of Cancer Targets
The "Mount Everest" of cancer genes, MYC, has been targeted by a new RNA degrader approach, where cellular recycling enzymes are directed to cancer gene RNA to remove key segments.
Echo® MS Center of Excellence Launches at SCIEX Headquarters
SCIEX, celebrates the opening of the Echo® MS Center of Excellence.
MIMETAS Launches Ready-To-Use 3D Adult Stem Cell Organoid Tubules
MIMETAS announces that it has launched its Adult Stem Cell (ASC)-derived tubular organoids in an assay-ready format.