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Screening Strategies in Drug Discovery – News and Features

Immunotherapy molecules fighting a cancer cell.
News

Virtual Drug Screening Identifies Candidates for Cancer Immunotherapy

Researchers at Weill Cornell used virtual screening to find small molecules targeting cancer checkpoints, showing promise as alternatives to monoclonal antibody treatments. The study identified compounds MG-T-19 and MG-V-53.
A caterpillar infected with Cordyceps militaris, the pretty orange fungus that produces Cordycepin.
News

Cordycepin From Caterpillar Fungus May Disrupt Cancer Cell Growth

Researchers discovered that cordycepin, derived from the caterpillar fungus Cordyceps militaris, disrupts cancer cell growth by interfering with signaling pathways. The compound converts to cordycepin triphosphate within cells, mimicking ATP.
A molecule inside a red and blue drug capsule
Industry Insight

Three Technologies Set To Transform Drug Discovery in 2025 and Beyond

Technology Networks asked a selection of startups featured in the ELRIG Drug Discovery 2024 Breakthrough Zone how their technology might reshape the pharmaceutical industry and pave the way for the next generation of therapeutic discovery.
Pseudomonas luteola on BTB agar.
News

How a Lung Pathogen Manages the Balance Between Colonizing and Surviving During Infection

A study by EPFL shows how Pseudomonas aeruginosa manages the trade-off between biofilm formation for antibiotic protection and a mobile state to spread in the lungs.
Scientists working in a lab.
Industry Insight

AI and Bioengineering: How Biotech Start-Ups Are Driving Innovations in Drug Discovery

We reached out to start-ups at ELRIG Drug Discovery 2024 to see how AI and bioengineering can be applied in biotech and drug discovery.
Lab scientists reviewing medical images
Industry Insight

Biotech Start-Ups Share How They Are Addressing Key Limitations in Disease Models

Technology Networks asked a selection of start-up companies at ELRIG Drug Discovery how their technology addresses key limitations in traditional disease models.
3D illustration of a cell showing the cell membrane and nucleus of the cell
Article

Cell Painting in Drug Discovery: A Conversation With Assay Pioneer Anne Carpenter

Technology Networks caught up with Dr. Anne Carpenter at ELRIG Drug Discovery 2024 to learn more about the Cell Painting assay and its impact on the pharmaceutical industry.
RNA Polymerase II transcribing DNA into RNA.
Industry Insight

Getting New Drug Modalities to Market: How Can Your Data Strategy Help?

This article explores the revolution in new drug modalities and the challenges around effective data strategies to support AI efforts.
A researcher pipettes clear liquid into a tube.
News

PFAS Are More Toxic Combined

A new study has measured the toxicity of several types of PFAS, better known as “forever chemicals,” when mixed together in the environment and in the human body.
Cancer cells.
News

Largest Collection of Sarcoma Patient-Derived Organoids Pave the Way for Personalized Cancer Treatments

A UCLA team created a biobank of sarcoma organoids from 126 patients, enabling rapid drug screening. The organoids retained tumor characteristics, allowing identification of effective FDA-approved treatments for 59% of samples.
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