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Single-Cell Analysis – News and Features

Four honeybees.

Genetic Mechanisms Underlying Bee Colony Aggression

What determines whether older bees become foragers or soldiers is unknown, but a new study explores the genetic mechanisms underlying the collective behavior of colony defense, and how these mechanisms relate to the colony’s overall aggression.

Interior view of red blood cells in a blood vessel.

How Some Blood Vessel-Modulating Drugs Cause Vascular Disease

Researchers say that certain drugs that block tumor growth can cause vascular injury by changing the vascular architecture and impeding correct blood flow.
A mosaic of cells in different colors, shapes and sizes.

Cancer Immune Cell Atlas Provides Detailed Picture of Tumor Environment

A new pan-cancer T cell atlas has provided insights into the vast diversity of T cell states, roles and relationships in the tumor microenvironment.
Axonal projections of sensory neurons stained with a fluorescent dye.

Swallowing Disorders' Links to the Vagus Nerve Identified

According to research, swallowing disorders could be a result of vagus nerve signal failure.
Coral reef.

Early Steps of Coral–Algae Symbiosis Revealed

New research reveals how coral cells tag friendly algae before ingesting them, initiating a mutually beneficial relationship. This information could guide next-level coral conservation efforts.
Plastic model of the lungs.

Cell Variants Identified in Lungs of Idiopathic Pulmonary Fibrosis Patients

Researchers have identified variant cells in the lungs of patients with Idiopathic Pulmonary Fibrosis, which could represent key targets in any future therapy for the condition.
A strand of DNA disintegrates into the letters of the nucleotides.

The Glue of Genomics: Will Science’s Unsung Data Heroes Abandon Academia?

This article will review the latest advances in next-generation sequencing technologies, data analysis tools and their various applications with key research examples.
Spatial transcriptomics method depicted in an image.

Cereal Crops Evolved by “Trading” Genetic Modules

Comparing individual cells across corn, sorghum, and millet reveals evolutionary differences among these important cereal crops, according to a new study led by New York University researchers.
Representation of human cells.

Diverse and Dynamic Senescent Cell Populations Uncovered

In this study, researchers set out to comprehensively analyze the senescent transcriptome of human diploid fibroblasts at the individual-cell scale by performing single-cell RNA-sequencing analysis through two approaches.
An illustration of the gut, filled with bacteria.

Gut Immune System of Children With IBD Mapped

Researchers have mapped the gut immune system in children with inflammatory bowel disease (IBD), which could aid in the development of more targeted therapies.