Single-Cell Analysis – News and Features
How Tumors Create Cancer-Promoting Immune Cells
According to research, soft-tissue sarcomas produce a protein that switches immune cells from tumor-attacking to tumor-promoting.
Dissecting the Complexity of the Brain at a Single-Cell Level
Understanding the brain requires an in-depth knowledge of its components. Advanced single-cell sequencing technologies are enabling researchers to explore the secrets of this complex and mysterious organ in unprecedented detail.
New Mechanism Causes Both Inflammation and Immunosuppression in Tumors
Researchers have identified the mechanism by which active inflammation occurs in parallel with immunosuppression in the tumor microenvironment.
Alternative Route That Cells Take To Make Organs Uncovered
Extra-embryonic stem cells have been used to identify an alternative route by which organs develop in the embryo.
Differentiation Protocol Could Improve Stem Cell-Based Therapies for Macular Degeneration
Scientists have tested and confirmed a protocol for growing human embryonic stem cells into retina cells to treat eye diseases such as age-related macular degeneration.
Mathematical Approach Shows Tumor mRNA Levels Predict Cancer Outcomes
Researchers have developed a new approach to quantify tumor-specific total mRNA levels from patient tumor samples, which could serve as a prognostic biomarker for many types of cancers.
Stress Protein Could Be a Good Target for Future Cancer Drugs
Inhibiting a stress protein that is upregulated in many different cancer types could provide a new strategy for future cancer drugs.
AI Distinguishes Cancer Cells From Healthy Ones
A machine learning program has been used to distinguish between cancerous and healthy cells by identifying patterns in characteristic combinations of genes.
Tying Human Genes to Their Function Using CRISPR Technology
Researchers have expanded on data from the Human Genome Project, using their single-cell sequencing tool – Perturb-seq – to link each human gene to its function and create a free resource for other researchers.
Heart Disease May Be Worsened by Aggressive T Cells
T cells that attack apolipoprotein B, the main component of "bad" cholesterol, could be contributing to inflammation that worsens heart disease.