Spatial Biology – News and Features

T-cell exhaustion can prevent optimal responses to immunotherapy, but a new cytokine "cocktail" may help increase T-cell survival.

New research explains why metastatic uveal melanoma is resistant to conventional immunotherapies and how adoptive therapy can successfully treat this rare and aggressive cancer.

A new study from Van Andel Institute scientists offers a first look into the complex molecular changes that occur in brain cells with Lewy bodies, which are key pathological hallmarks of Parkinson’s disease and some dementias.

An international team of scientists has published the first single-cell atlas forPristina leidyi (Pristina), a segmented annelid with extraordinary regenerative abilities that has fascinated biologists for more than a century.

Examining the immune cells in the environment around a tumour could help to predict how a person’s cancer might progress and respond to treatment, according to new research led by UCL and the Francis Crick Institute.

A previously overlooked type of immune cell allows SARS-CoV-2 to proliferate, Stanford Medicine scientists have found. The discovery has important implications for preventing severe COVID-19.

Researchers have made a significant advancement toward understanding how the human genome is organized inside a single cell.

Researchers have identified microbiota signatures associated with KRAS mutations in people diagnosed with colorectal cancer. The findings suggest that gut microbes may serve as a kind of non-invasive biomarker for identifying subtypes of CRC.

A new “atlas” of the human ovary provides insights that could lead to treatments restoring ovarian hormone production and the ability to have biologically related children, according to University of Michigan engineers.

A University of Oklahoma researcher recently advanced the knowledge of pancreatic cancer with a study about how it acclimates to and even thrives in a highly acidic environment.