Spatial Biology – News and Features

BIDMC investigators make the surprising discovery that a gene associated with speech and language is linked to advanced breast cancer.

Findings suggest sequencing a single region of a localized tumor will identify driver mutations.

Distinct patterns of gene expression in several groups of CTCs were identified, including significant differences from the primary tumor that may contribute to the ability to generate metastases and prove to be targets for improved treatment of the deadly tumor.

The new system, called a tumor-microenvironment-on-chip device, will allow researchers to study the complex environment surrounding tumors and the barriers that prevent the targeted delivery of therapeutic agents.

UCSF researchers use microfluidic technology to probe human brain development.

Prototypes of the product are expected to begin shipping to early access partners by the end of this year.

Incorporation of algorithms modeling additional biological phenomena leads to predictive discovery of four potential immunomodulatory targets.

Discovery makes it possible for researchers to explore how these “precocious” cells escalate the body’s immune response when the body is under attack.

Scientists from the Broad Institute and Massachusetts General Hospital (MGH) have conducted a first-of-its-kind study that characterizes the cellular diversity within glioblastoma tumors from patients.