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Synthetic Biology – News and Features

Stands of DNA with green coding overlay.

Genome Recording Strategy Enables Cells To Keep a History of Past Events

A new genome recording strategy aims to turn cells into their own historians, by storing information about transient biological events inside living cells.
Illustration of hands using tweezers and scissors to edit DNA.

Novel CRISPR Method Teaches Gene Scissors To Detect RNA

CRISPR-Cas systems have become a plentiful source of technologies for molecular diagnostics and researchers have now developed a novel method that enables the detection of RNA with Cas12 nucleases, which naturally target DNA.
3D protein molecules showing the molecular backbone

An Introduction to Protein Purification: Methods, Technologies and Applications

The ability to obtain pure proteins is essential for developing drugs, creating vaccines and understanding biological processes. In this article, we discuss what a typical protein purification protocol involves and the various techniques used.

Researchers Dissect How Fluctuating Energy Sources Drive Microbial Bioproduction

In the work of biomanufacturing, tanks of microbes are fine-tuned to produce compounds that can be used as carbon-neutral fuels, chemicals, materials and medicines, but researchers are still learning the basics of how to turbo charge for production.
White, blue and grey icons on a blue background representing the future of drug discovery. Icons include pie charts, a DNA double helix, a drug capsule, artificial intelligence and cells.

How AI Is (So Close to) Transforming Drug Discovery

In this opinion piece, Markus Gershater provides a comprehensive look into the current state and immense potential of artificial intelligence in reshaping the landscape of drug discovery.
Yersinia enterocolitica.

A Cutting-Edge Approach to Bacterial DNA Manipulation

A team led by the Helmholtz Institute for RNA-based Infection Research (HIRI) in Würzburg has now introduced a novel approach that can make many more bacteria amenable to genetic engineering.
A close up of a rice plant.

CRISPR Technology Used To Edit Photosynthesis for the First Time

A team from the Innovative Genomics Institute at the University of California, Berkeley (UCB) has produced an increase in gene expression in a food crop by changing its upstream regulatory DNA.
ARRALYZE glass array with three different shaped wells highlighted. Each well is enlarged to display a different type of cell.
Industry Insight

Navigating the Complexities of Single-Cell Research

The advent of single-cell analysis has marked a transformative era in the life sciences, particularly in the field of drug development. To delve deeper into the subject, Technology Networks spoke with Dr. Nora Fekete-Drimusz, head of biology at ARRALYZE. We discuss the transformative impact of single-cell analysis on life science research and explore how ARRALYZE's multifunctional single-cell platform can support those working in this area.
A futuristic-style illustration of a trophy on a dark blue background.
Industry Insight

SLAS Europe 2024 New Product Award: Top Contenders Announced

Finalists for the New Product Award at the SLAS Europe conference showcase cutting-edge innovations in life sciences, evaluated on technical merit, commercial feasibility, originality, impact and market opportunity. Here, we take a look at the six nominees and the products competing for this year’s award.
Synthetic biologists inserted genes from the soap bark tree and other organisms into yeast to create a biosynthetic pathway for building a complex molecule called QS-21, a powerful adjuvant used in vaccines. The chemical structure of QS-21 is in the background.

Vaccine Adjuvant Made in Yeast Could Lower Costs and Boost Availability

Many vaccines, including the Novavax COVID-19 vaccine, contain adjuvants that stimulate the immune system to mount a stronger defense. Producing one such adjuvant in yeast promises to make it less expensive and more widely available.