The Immune System – News and Features

A UVA Cancer Center study shows that blood cancer patients who receive partially matched stem cell transplants have survival outcomes comparable to those with fully matched donors.

Scientists created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, specialize or turn cancerous.

Scientists identified a previously unknown gateway into human cells, a receptor called AAVR2, that gene therapy viruses use to deliver therapeutic genes. This newly uncovered pathway could allow lower doses of virus to be used in treatment.

A 24-year study of more than 1.2 million Danish children adds to the already considerable evidence finding no tie between exposure to aluminum-adjuvanted childhood vaccines and autoimmune, atopic or allergic or neurodevelopmental conditions.

UConn researchers have linked major depression to Alzheimer’s risk via disrupted protein regulation and inflammation. Their new Proteomic Risk Score outperforms existing models, predicting dementia in at-risk individuals.

Researchers from the universities of Basel and Zurich have used a historical specimen from UZH’s Medical Collection to decode the genome of the virus responsible for the 1918–1920 influenza pandemic in Switzerland.

Scientists have found that mesenchymal stromal cells, or MSC therapy, in combination with antiviral drugs, helped cats’ immune systems recover and reduced systemic inflammation.

A new study has found that early-life exposure to antibiotics can impair an infant's developing immune system, and that a naturally occurring metabolite may hold the key to reversing the damage.

Researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell therapy, or CAR T-cell therapy. Over time, the engineered immune cells age and lose their ability to fight cancer.

Karolinska Institutet scientists identified over 250 blood proteins altered by malaria, offering insight into disease severity. The study followed 72 adults and revealed protein signatures that could predict which patients are most at risk.