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The Immune System – News and Features

Multiple labeled blood bags arranged in a row, prepared for blood transfusion procedures.
News

Transplants Without a Full Match Now a Viable Treatment Path

A UVA Cancer Center study shows that blood cancer patients who receive partially matched stem cell transplants have survival outcomes comparable to those with fully matched donors.
A digital illustration of red blood cells flowing across a pink background.
News

Scientists Create First Integrated Map of Blood Stem Cell Metabolism

Scientists created the first integrated map detailing the metabolic and molecular changes in human blood stem cells as they age, specialize or turn cancerous.
A scientist holding up a test tube in front of a model of a DNA double helix, representing gene therapy.
News

Previously Unknown Gateway Into Cells Could Make Gene Therapies Safer

Scientists identified a previously unknown gateway into human cells, a receptor called AAVR2, that gene therapy viruses use to deliver therapeutic genes. This newly uncovered pathway could allow lower doses of virus to be used in treatment.
A doctor placing a plaster on the arm of a child who has just received a vaccination.
News

No Link Between Aluminum-Adjuvanted Childhood Vaccines and Autism

A 24-year study of more than 1.2 million Danish children adds to the already considerable evidence finding no tie between exposure to aluminum-adjuvanted childhood vaccines and autoimmune, atopic or allergic or neurodevelopmental conditions.
Silhouetted person sitting alone in a dim hallway, head down, reflecting symptoms of depression.
News

How Depression Drives Alzheimer’s Risk – And What Can Be Done

UConn researchers have linked major depression to Alzheimer’s risk via disrupted protein regulation and inflammation. Their new Proteomic Risk Score outperforms existing models, predicting dementia in at-risk individuals.
Emergency hospital in Zurich's Tonhalle during the so-called “Spanish flu” in November 1918.
News

Spanish Flu Virus Genome Reconstructed After 100 Years

Researchers from the universities of Basel and Zurich have used a historical specimen from UZH’s Medical Collection to decode the genome of the virus responsible for the 1918–1920 influenza pandemic in Switzerland.
Tabby cat is cared for by Clinical Trials Coordinator after receiving treatment as part of a clinical trial on FIP at UC Davis School of Veterinary Medicine.
News

Lessons on Long COVID From Feline Coronavirus

Scientists have found that mesenchymal stromal cells, or MSC therapy, in combination with antiviral drugs, helped cats’ immune systems recover and reduced systemic inflammation.
A new born baby's feet.
News

Early Antibiotic Use Alters Infant Immune Development

A new study has found that early-life exposure to antibiotics can impair an infant's developing immune system, and that a naturally occurring metabolite may hold the key to reversing the damage.
3D illustration of CAR T cells attacking a cancer cell, highlighting cellular aging processes.
News

CAR T-Cell Aging Linked to Cancer Relapse

Researchers have discovered a key reason some cancer patients relapse after receiving chimeric antigen receptor T-cell therapy, or CAR T-cell therapy. Over time, the engineered immune cells age and lose their ability to fight cancer.
Mosquito standing on a light surface, symbolizing malaria transmission risk.
News

Karolinska Study Links 250+ Proteins to Malaria Outcomes

Karolinska Institutet scientists identified over 250 blood proteins altered by malaria, offering insight into disease severity. The study followed 72 adults and revealed protein signatures that could predict which patients are most at risk.
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