The Immune System – News and Features

News
Disrupting the Cell Feedback Loop Fueling Leukemia
Researchers have identified a signaling loop involved in the growth and persistence of leukemia cells, and developed a novel immunotherapy that can disrupt that loop to boost immune function and improve survival.

Article
A Guide to Glycan Analysis of Therapeutic Glycoproteins
Discover what glycan analysis can reveal about protein behavior and how it can be used to boost biologic performance and ensure therapeutic quality in biopharmaceutical drug development.

News
Heavy Metals Linked to Stunted Growth in Infants in Guatemala
The study found a potential link between growth problems among infants and high levels of toxic metals and other elements in the breast milk of Mayan women in Guatemala’s Lake Atitlán watershed region.

News
Microglia Replacement Therapy Halts Progressive Neurological Disease
Replacing mutated microglia with healthy microglia halts the progression of the genetic neurological disease adult-onset leukoencephalopathy with axonal spheroids and pigmented glia in mice and humans.

News
Microchip Accelerates Antibody Mapping for Faster Vaccine Design
By analyzing just a drop of blood, a novel microchip system, known as microfluidic EM-based polyclonal epitope mapping, gives researchers quicker-than-ever insight into how a person’s antibodies are interacting with a virus or other pathogen.

News
How B Cells Remember the Flu: The Role of T-bet
Using detailed genetic analysis and manipulation, researchers show that continuous T-bet expression in these cells is key to preserving the protective memory response.

News
“Molecular Shield” in the Nose Blocks Hay Fever Reactions
Researchers developed a nasal antibody that blocks mugwort pollen, a major hay fever trigger in Europe and Central Asia. Delivered intranasally, it reduced allergic symptoms and inflammation in mice without systemic side effects.

News
HPV Vaccine Shows Sustained Real-World Impact in Denmark
The results offer real-world data that support long-term protection through vaccination and suggest a level of population immunity.

News
Promising Drug Candidates Selectively Target Nerve Pain Receptors
Scientists have discovered novel drug candidates that could ultimately lead to new effective treatments for conditions caused by tissue stress and inflammation, including neuropathic pain and ischemia-reperfusion injury.

News
Study Finds Link Between Premenstrual Symptoms and Heart Disease
Women diagnosed with premenstrual symptoms have a slightly increased risk of developing cardiovascular disease later in life. This is shown by a new study from Karolinska Institutet published in Nature Cardiovascular Research.
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