The Immune System – News and Features

Scientists have developed a new paper-based device that can improve the diagnosis of malaria in asymptomatic people. In field tests in Ghana, the device outperformed the current gold standard methods being used in the country's hospitals.

Transplanting healthy human glial progenitor cells into the brains of adult animal Huntington's disease models not only slowed motor and cognitive decline but also extended lifespan.

Pembrolizumab, an immune checkpoint inhibitor, has been approved by the US Food and Drug Administration for the treatment of patients with resectable locally advanced head and neck squamous cell carcinoma whose tumors express PD-L1.

New research sheds light on the mechanisms of degeneration in multiple sclerosis, suggesting that mitochondrial dysfunction may play a key role in the loss of neuronal Purkinje cells.

Researchers have found that this immune “tolerance” to gut microbes depends on an ancient bacterial-sensing protein called STING – normally considered a trigger for inflammation.

A new meta-analysis has revealed that the Parkinson's gut microbiome is unusually enriched in genes involved in breaking down chemicals, such as pesticides and pollutants.

Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology — potentially opening the door for better-designed therapeutics.

A study shows that women with BRCA1 or BRCA2 mutations who have textured breast implants are at a 16-fold higher risk of developing lymphoma. The findings stress the importance of genetic testing and informed decision-making.

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets. Researchers have now developed a method for tracking these cells in the body.

A study shows how a class of drugs, HDACi (histone deacetylase inhibitors), protects neurons and limits brain damage following stroke by altering the gene expression of microglia, the immune cells of the brain.