The Immune System – News and Features

A new meta-analysis has revealed that the Parkinson's gut microbiome is unusually enriched in genes involved in breaking down chemicals, such as pesticides and pollutants.

Two key protein structures in the body are being visualized for the first time, thanks in part to the latest technology — potentially opening the door for better-designed therapeutics.

A study shows that women with BRCA1 or BRCA2 mutations who have textured breast implants are at a 16-fold higher risk of developing lymphoma. The findings stress the importance of genetic testing and informed decision-making.

In modern immunotherapy, modified immune cells are introduced into the body to attack tumors and other targets. Researchers have now developed a method for tracking these cells in the body.

A study shows how a class of drugs, HDACi (histone deacetylase inhibitors), protects neurons and limits brain damage following stroke by altering the gene expression of microglia, the immune cells of the brain.

In a 13-year follow-up by St. Jude Children’s Research Hospital and University College London published in The New England Journal of Medicine, researchers demonstrate the long-term viability of gene therapy for the treatment of hemophilia B.

Research shows that the drug tazemetostat – which is already approved for use in patients with one type of B-cell lymphoma – could work better when combined with another targeted drug and for patients with the most common type of B-cell lymphoma.

Many types of bacteria produce a protein complex that injects toxins into neighboring cells to eliminate competitors. For the first time, researchers discovered that these killer bacteria also use this weapon to feed on their neighbors.

Researchers have elucidated at least one mechanism of breast cancer cell proliferation and migration. With the discovery, they may have also uncovered how short chains of protein building blocks could serve as a novel anticancer drug.

This article explores how next-generation sequencing has revolutionized microbiome research, enabling comprehensive analysis of microbial communities and their roles in health and disease.