The Immune System – News and Features

A study led by biomedical scientists at the University of California, Riverside School of Medicine shows how a genetic mutation associated with Crohn’s disease can worsen iron deficiency and anemia.

UConn researchers have demonstrated that a novel protein-based nanoparticle can make mRNA vaccines more effective in tackling a troublesome pathogen in chickens.

Researchers at UC San Diego discovered that itaconate, a metabolite known for immune roles in animals, is produced in plants. It helps stimulate growth and supports plant processes such as metabolism and stress response.

Estradiol, the most potent form of estrogen during a woman’s reproductive years, may help protect the brain as it ages, as a new study finds that women with a longer reproductive span showed signs of slower brain aging.

Researchers have discovered a novel biomarker for severe multiple sclerosis (MS). This research will contribute to our understanding of the molecular processes involved in progressive MS, and may aid in the allocation of patients to novel therapies.

Researchers at the University of Cincinnati are exploring ways to interrupt the lifecycle of the parasite behind Chagas disease, offering hope of developing a cure.

New research shows how metabolic activity and thus the communication between intestinal tissue and microbiome collapses during intestinal inflammation.

New research has found that adding IL-12, a cytokine produced by various immune cells, to mRNA vaccines improves T-cell responses. This could make the benefits of vaccines last longer.

This article explores the current landscape and future potential of cell therapies, including CAR T-cell and stem cell-based approaches, highlighting their expanding clinical use, underlying mechanisms and the challenges that lie ahead.

Inspired by the way viruses attach to cells, scientists have developed a method for engineering ultra-selective aptamers. These synthetic molecules bind to specific targets like viral spike proteins, making them useful for diagnostics and treatments.