Therapeutic Antibodies – News and Features

A breakthrough has occurred in pinpointing the underlying cause of preeclampsia (PE). Researchers analyzed protein content in the placenta and serum of PE patients, discovering increased levels of the protein cis P-tau.

A new study from the Massachusetts Institute of Technology has investigated why checkpoint blockade inhibitors - a type of immunotherapy - don't always work as expected.

Antibody treatments may be able to activate the immune system to fight diseases but are less effective when they bind with themselves. Now, new machine-learning algorithms can highlight problem areas in antibodies.

A research team is looking beyond antibody therapeutics for cancer, leading new studies into how "helper" T cells can detect and help destroy cancer cells.

Studies have shown that lecanemab slows cognitive and functional decline in early-stage Alzheimer’s patients. But as with many other cutting-edge therapies, we know more about lecanemab’s effectiveness than we do about how it actually works.

An international phase 3 clinical trial, found that a new targeted treatment called zolbetuximab, given in combination with a standard chemotherapy, extended survival for patients with advanced gastric or gastroesophageal junction cancer.

Two sisters have been involved in the UK's first uterine transplant. The case report is published in the journal BJOG: An International Journal of Obstetrics & Gynaecology.

Research and Development costs for targeted oncology drugs are markedly lower if guided by a companion diagnostic strategy, but current biopharmaceutical business models suggest these savings will not be reflected in more affordable pricing.

The FDA has given the green light to Elrexfio™ (elranatamab-bcmm), granting it accelerated approval to treat adults with multiple myeloma – a type of blood cancer – who have received at least four previous rounds of certain therapies.

A new study has illustrated that patients with a high BMI are at higher risk of heart damage during cancer treatment.