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This lecture will review the latest advances in volatile analyses for disease diagnosis.

Apart from diagnostic devices, microfluidic devices are increasingly used to realise advance disease and organ-models, as illustrated by the blood-brain barrier chip and a blood vessel on a chip.

We report on the development of a modified commercial DVD reader with all the necessary components required for a truly integrated lab-on-a-chip system, with the capability to deliver high-resolution images down to 1 μm in size.

A complementary cell analysis method has been developed to assess the dynamic interactions of tumor cells with resident tissue and immune cells using optical light scattering and impedance spectroscopy to shed light on tumor cell behavior.

The need to successfully deposit very small volumes of biological and chemical content on devices exists across a wide range of applications, in research and diagnostics, such as microarray spotting on glass surfaces, and depositing samples on pre-defined microfluidics targets.

This talk highlights novel strategies for the detection of single molecules using multiphase microfluidics.

Microfluidic and nanotechnological systems on chip exhibit the potential of cell based analysis especially pathogen detection on chip.

We first report on a magnetic surface coverage assay, in which ‘large’ (2.8 μm) magnetic beads have contact with ‘small’ (1.0 μm) immobilized magnetic beads via magnetic dipolar interaction to induce specific immunocomplex formation.

As many biodetection assays, especially nucleic-acid based tests, require a more or less complex sample preparation protocol, microfluidics is seen as one of the key enabling technologies to realize the integration of these sample prep protocols with the detection scheme on a single device.