The proteome is the most functional component encoded for in the genome. Advances in proteomic technologies allow comprehensive profiling of of signaling pathways, precise expression of therapeutic targets in tissues and cellular subcompartments, and of metabolomic features that determine likelihood of therapeutic response. Moreover the current paradigm shift in cancer therapy with dramatic and durable responses to antibody and checkpoint therapeutics that trascend tumor genomic profiles further emphasize opportunities to identify novel targets and tailor treatment based on their expression patterns. The potential for personalizing cancer treatment based on proteomic and metabolomic profiles will be presented for epithelial type tumors including lung and pancreatic cancer.
Beyond Genomics For Personalized Medicine
Video Sep 19, 2016
How Does Your Body Process Medicine?Video
Have you ever wondered what happens to a painkiller, like ibuprofen, after you swallow it? Medicine that slides down your throat can help treat a headache, a sore back, or a throbbing sprained ankle. But how does it get where it needs to go in the first place?WATCH NOW
Bees Under Siege: Making Sense of Multiple StressorsVideo
Bees are an important link in the global food-chain. However, modern agricultural practices, chemicals, predators, diseases: they are all damaging to bees. But what happens when bees are exposed to more than one stressor simultaneously? EFSA is trying to find out.WATCH NOW