The proteome is the most functional component encoded for in the genome. Advances in proteomic technologies allow comprehensive profiling of of signaling pathways, precise expression of therapeutic targets in tissues and cellular subcompartments, and of metabolomic features that determine likelihood of therapeutic response. Moreover the current paradigm shift in cancer therapy with dramatic and durable responses to antibody and checkpoint therapeutics that trascend tumor genomic profiles further emphasize opportunities to identify novel targets and tailor treatment based on their expression patterns. The potential for personalizing cancer treatment based on proteomic and metabolomic profiles will be presented for epithelial type tumors including lung and pancreatic cancer.
Beyond Genomics For Personalized Medicine
Video Sep 19, 2016
Our genetic makeup has fascinated scientists and medical researchers for decades. There have been significant advances in the field of rewriting the blueprint of life or our DNA. It's been used to treat and prevent a number of disorders and diseases. But it could also be used to create what some have called 'designer babies'. The medical world is divided over the approach. Last year, a scientist in China said he created the world's first genetically edited twins -- leading to global condemnation. Scientists have gathered in Geneva this week to try come up with some regulations. But how would officials enforce rules around our DNA? And what are the risks of advanced research into human genetics?WATCH NOW