Methods are urgently required to validate and improve these draft assemblies. We have developed several approaches to assess the quality of draft genome assemblies, identify regions of misassembly and correct assemblies. These approaches can be applied to a broad range of genomes which have either been completed or are undergoing development. In addition, we have developed methods for high resolution SNP discovery for the assessment of genome evolution and trait association in complex crop genomes. I will give examples of these applications to plant genomes of different size and complexity.
Characterising Plant Genomes The Good The Bad and The Ugly
Video Mar 30, 2015
It may seem that rabbits that walk with their hind legs over their head--like an acrobat walking on her hands--belong in a circus, but this breed spends almost all the time in a lab. By comparing these sauteur d’Alfort with run-of-the-mill breeds, researchers are learning what it takes to move limbs in a coordinated way. Now, they have pinned down the single genetic mutation that likely causes this peculiar form of locomotion.WATCH NOW