Methods are urgently required to validate and improve these draft assemblies. We have developed several approaches to assess the quality of draft genome assemblies, identify regions of misassembly and correct assemblies. These approaches can be applied to a broad range of genomes which have either been completed or are undergoing development. In addition, we have developed methods for high resolution SNP discovery for the assessment of genome evolution and trait association in complex crop genomes. I will give examples of these applications to plant genomes of different size and complexity.
Characterising Plant Genomes The Good The Bad and The Ugly
Video Mar 30, 2015
The PromethION is Oxford Nanopore Technologies' largest sequencing device, capable of delivering many terabases of data, in real time, from a single run. Hear how teams across a broad range of applications, based in labs all over the world — US (UCSF, UCD, JCVI and UCSC), China (GrandOmics and Biomarker) and Europe (KeyGene, Genescope and UMC Utrecht) — are using PromethION in their work.WATCH NOW
Northwestern University and Washington University School of Medicine researchers have developed the first example of a bioelectronic medicine: an implantable, biodegradable wireless device that speeds nerve regeneration and improves healing of a damaged nerve. Their device delivered pulses of electricity to damaged nerves in rats after a surgical repair process, accelerating the regrowth of nerves and enhancing the recovery of muscle strength and control. The device is the size of a dime and the thickness of a sheet of paper and dissolves in the body after about two weeks.