Mass spectrometry can be useful to overcome many of the limitations of immunoassays, which are mainly but not only due to cross-reactivity with structurally related compounds. The talk will discuss how the improvements in the measurement of glucocorticoids and mineralocorticoids obtainable by well validated mass spectrometry methods are translated into clinical relevant information for the evaluation and management of hypothalamic-pituitary-adrenal axis disorders. Among others, mass spectrometry may be useful to avoid clinical uncertainties derived from immunoassay based results and, at the same time, it allows the obtaining of a more complete view of the steroidogenic status of the patients by means of steroid profiling.
Contributions of Mass Spectrometry in the Diagnosis and Management of Hypothalamic–pituitary–adrenal Axis Disorders
Video Mar 31, 2015
Only 17% of the English-language biographies on Wikipedia are about women – but the statistic won’t stay that low for long if Dr Jess Wade has her way. A passionate advocate for diversity in science, Jess balances her work as an award-winning physicist at Imperial College London with her role as a ‘Wikipedian’, creating and uploading the biographies of underrepresented groups in science.WATCH NOW