Mass spectrometry can be useful to overcome many of the limitations of immunoassays, which are mainly but not only due to cross-reactivity with structurally related compounds. The talk will discuss how the improvements in the measurement of glucocorticoids and mineralocorticoids obtainable by well validated mass spectrometry methods are translated into clinical relevant information for the evaluation and management of hypothalamic-pituitary-adrenal axis disorders. Among others, mass spectrometry may be useful to avoid clinical uncertainties derived from immunoassay based results and, at the same time, it allows the obtaining of a more complete view of the steroidogenic status of the patients by means of steroid profiling.
Contributions of Mass Spectrometry in the Diagnosis and Management of Hypothalamic–pituitary–adrenal Axis Disorders
Video Mar 31, 2015
For scientists whose research requires high-precision isotope ratio data in fields of cosmo- and geochemistry, geochronology and biology, nuclear safeguards, forensics, metalomics, and provenance studies, we have created a new multicollector ICP-MS. Designed and developed in Bremen, building on the strengths of our multi-collector platform with field-proven technologies such as RPQ, 10^13 ohm Amplifier Technology and Jet Interface.WATCH NOW
Urinalysis has long been a staple of physical exams to detect and manage a number of diseases and disorders, but not cancer. What if it were that easy, though, and cancer was detected in its very earliest stages when the disease responds more favorably to treatment and improved outcomes are more likely?WATCH NOW