Mass spectrometry can be useful to overcome many of the limitations of immunoassays, which are mainly but not only due to cross-reactivity with structurally related compounds. The talk will discuss how the improvements in the measurement of glucocorticoids and mineralocorticoids obtainable by well validated mass spectrometry methods are translated into clinical relevant information for the evaluation and management of hypothalamic-pituitary-adrenal axis disorders. Among others, mass spectrometry may be useful to avoid clinical uncertainties derived from immunoassay based results and, at the same time, it allows the obtaining of a more complete view of the steroidogenic status of the patients by means of steroid profiling.
Contributions of Mass Spectrometry in the Diagnosis and Management of Hypothalamic–pituitary–adrenal Axis Disorders
Video Mar 31, 2015
Our Behind the Science host Jen goes back to our new 2D-LC lab to meet Claude Mallet, Ph.D., a senior scientist at Waters, and Sabra Botch-Jones, M.S., M.A., D-ABFT-FT, an assistant professor in the department of Anatomy & Neurobiology, Biomedical Forensic Sciences, at Boston University School of Medicine (http://www.bumc.bu.edu/gms/msci/about...) to learn how her lab uses 2DLC.WATCH NOW
8th Edition of International Conference and Exhibition on Separation Techniques
Jul 29 - Jul 30, 2019
12th Edition of International Conference on Infectious Diseases
Apr 22 - Apr 23, 2019