Deciphering the Molecular Pathology of Alzheimer’s Disease

Video   Feb 08, 2017

 
 
 

Alzheimer’s disease presents stereotypical pathological features including the abundance of amyloid deposition and tauopathy. Affected brain regions also exhibit reactive astrogliosis, neuroinflammatory responses, and vascular pathology. Neuronal and synaptic loss is also evident. Various mouse lines have been created to investigate Alzheimer’s disease and most of the models exhibit a subset of the defining pathological features of the disease. In this webinar the speaker will discuss the use of Alzheimer’s disease transgenic mouse models to evaluate pathological features by both traditional immunohistochemistry and new tissue processing methods that enable whole- brain imaging. These immunolabeling methods further the investigation of molecular and neural circuit mechanisms of Alzheimer’s disease.

 
Company Information
 
 
 

Recommended Videos

Brain Uses Novel RIP3K Signalling to Fight-Off West Nile Virus

Video

Researchers describe their findings that RIP3K is neuroprotective upon West Nile virus infection

WATCH NOW

Flight of the Navigator

Video

Video by Jim Gorman of the New York Times explains how researchers in Vivek Jayaraman's lab at Janelia Research Campus are exploring the neurophysiology of movement and direction.

WATCH NOW

Marching for Science in London

Video

Hear from the organisers, speakers, and protesters at London's March for Science.

WATCH NOW

 

Comments | 0 ADD COMMENT

Like what you just watched? You can find similar content on the communities below.

Neuroscience

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE