Deciphering the Molecular Pathology of Alzheimer’s Disease

Video   Feb 08, 2017

 

Alzheimer’s disease presents stereotypical pathological features including the abundance of amyloid deposition and tauopathy. Affected brain regions also exhibit reactive astrogliosis, neuroinflammatory responses, and vascular pathology. Neuronal and synaptic loss is also evident. Various mouse lines have been created to investigate Alzheimer’s disease and most of the models exhibit a subset of the defining pathological features of the disease. In this webinar the speaker will discuss the use of Alzheimer’s disease transgenic mouse models to evaluate pathological features by both traditional immunohistochemistry and new tissue processing methods that enable whole- brain imaging. These immunolabeling methods further the investigation of molecular and neural circuit mechanisms of Alzheimer’s disease.

 
More Information
 
 
 

Recommended Videos

How Dangerous Are Concussions?

Video

Each year in the United States, players of sports and recreational activities receive between 2.5 and 4 million concussions. How dangerous are all those concussions?

WATCH NOW

The Anatomy of a Neuron

Video

Introduction to the neuron and its anatomy from the Khan Academy

WATCH NOW

How do drugs affect the brain?

Video

Sara Garofalo explains how some drugs can alter the communication between cells in the brain.

WATCH NOW

 

Comments | 0 ADD COMMENT

Like what you just watched? You can find similar content on the communities below.

Neuroscience

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE