We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Advertisement

Genetic Dissection of Wheat-Necrotrophic Pathogen Interactions

Video   Dec 16, 2014

 

Stagonosporanodorum is a necrotrophic pathogen of wheat, and over the past decade, we have dissected the genetic components of the wheat-S. nodorumpathosystem. S. nodorum produces numerous host-selective toxins (HSTs) that interact with specific dominant host genes in an inverse gene-for-gene manner to cause disease.  In recent years, we have cloned the wheat genes Tsn1 and Snn1, which recognize the HSTs SnToxA and SnTox1, respectively, leading to susceptibility. Tsn1 is a member of the NB-LRR class of disease ‘resistance’ genes, which typically activate effector-triggered immunity (ETI) in response to biotrophic pathogens, and Snn1 is a wall-associated kinase (WAK), which is a class of receptor kinases known to activate PAMP-triggered immunity (PTI) pathways in response to biotrophic pathogens. Indeed, recognition of SnToxA and SnTox1 by Tsn1 and Snn1 activates a defense response and programmed cell death, but because the pathogen is a necrotroph, it is able to gain nutrients and sporulate, which leads to disease. These results demonstrate that necrotrophic pathogens such as S. nodorum can hijack host molecular pathways driven by different classes of genesthat typically confer resistance to biotrophic pathogensthus revealing the remarkably sophisticated nature of plant-necrotrophic pathogen interactions.

 
 
 
Advertisement
 

Recommended Videos

MRI Scans of Fruits and Veggies

Video

Watch as an MRI machine produces hypnotic images of various fruits and veggies.

WATCH NOW

Teach Me in 10 – How Big Data and AI Can Accelerate R&D With Dr Pillhun Son

Video

In this installment of Teach Me in 10, Pillhun Son explains exactly how Big Data and AI can accelerate research and development.

WATCH NOW

Teach Me in 10 – Why Synthetic Biology Will Eat Your Fields With Dr Jake Wintermute

Video

In this installment of Teach Me in 10, Dr Wintermute provides a Synthetic Biology 101, teaching you everything that you need to know about this interesting area of science, in less than 10 minutes.

WATCH NOW

 

Like what you just watched? You can find similar content on the communities below.

Genomics Research

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE