We've updated our Privacy Policy to make it clearer how we use your personal data.

We use cookies to provide you with a better experience, read our Cookie Policy

Genetic Dissection of Wheat-Necrotrophic Pathogen Interactions

Video   Dec 16, 2014

 

Stagonosporanodorum is a necrotrophic pathogen of wheat, and over the past decade, we have dissected the genetic components of the wheat-S. nodorumpathosystem. S. nodorum produces numerous host-selective toxins (HSTs) that interact with specific dominant host genes in an inverse gene-for-gene manner to cause disease.  In recent years, we have cloned the wheat genes Tsn1 and Snn1, which recognize the HSTs SnToxA and SnTox1, respectively, leading to susceptibility. Tsn1 is a member of the NB-LRR class of disease ‘resistance’ genes, which typically activate effector-triggered immunity (ETI) in response to biotrophic pathogens, and Snn1 is a wall-associated kinase (WAK), which is a class of receptor kinases known to activate PAMP-triggered immunity (PTI) pathways in response to biotrophic pathogens. Indeed, recognition of SnToxA and SnTox1 by Tsn1 and Snn1 activates a defense response and programmed cell death, but because the pathogen is a necrotroph, it is able to gain nutrients and sporulate, which leads to disease. These results demonstrate that necrotrophic pathogens such as S. nodorum can hijack host molecular pathways driven by different classes of genesthat typically confer resistance to biotrophic pathogensthus revealing the remarkably sophisticated nature of plant-necrotrophic pathogen interactions.

 
 
 
 

Recommended Videos

Invitrogen™ Collibri™ NGS Library Preparation Kits for Illumina™ Systems

Video

Watch the benefits of visual feedback at each step in the protocol. The colored dyes indicate proper addition and mixing of reagents with the Invitrogen Collibri DNA library preparation kits for Illumina systems.

WATCH NOW

Genes in the Enivornment

Video

Under the influence of longer-term climate change, crop growing conditions are becoming more extreme.

WATCH NOW

Rainforests 101 - National Geographic

Video

Rainforests are home to over half of the world's plant and animal species. Learn about tropical and temperate rainforests, how they contribute to the global ecosystem, and the conservation efforts being done to protect these biomes.

WATCH NOW

 

Like what you just watched? You can find similar content on the communities below.

Genomics Research

To personalize the content you see on Technology Networks homepage, Log In or Subscribe for Free

LOGIN SUBSCRIBE FOR FREE