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Ketamine as an Antidepressant With Dr. Lisa Monteggia

In some patients, the rapid antidepressant action of ketamine can last for days, or even weeks. This, says Dr. Lisa Monteggia, is incredible for a drug that is cleared from the body very quickly. Over recent years, The Monteggia laboratory at Vanderbilt University has been investigating the molecular mechanisms that underly this rapid action. In this Teach Me in 10, Dr. Monteggia outlines some of the key discoveries that her team have made, particularly in relation to ketamine, neuroplasticity and neuroreceptors.